The Mobile Phase Motion in Ascending Micellar Thin-Layer Chromatography with Normal-Phase Plates

被引：5

作者：

Boichenko, Alexander P. ^{[1
]}

Makhno, Iryna V. ^{[3
]}

Renkevich, Anton Yu. ^{[2
]}

Loginova, Lidia P. ^{[2
]}

机构：

[1] Univ Groningen, Univ Ctr Pharm, Dept Analyt Biochem, NL-9713 AV Groningen, Netherlands

[2] Kharkov VN Karazin Natl Univ, Dept Chem Metrol, UA-61077 Kharkov, Ukraine

[3] Kharkov Pharmaceut Plant Zdorove Narodu Co Ltd, UA-61013 Kharkov, Ukraine

来源：

JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC | 2011年 / 24卷 / 06期

关键词：

Micellar thin-layer chromatography; Viscosity; Surface tension; Motion; Model; ALIPHATIC CARBOXYLIC-ACIDS; LIQUID-CHROMATOGRAPHY; PAPER CHROMATOGRAPHY; HYDROPHILIC VITAMINS; LOW VOLATILITY; FLOW VELOCITY; AMINO-ACIDS; SEPARATION; SURFACTANTS; MIGRATION;

D O I：

10.1556/JPC.24.2011.6.2

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The physical chemical characteristics (surface tension and viscosity) of micellar mobile phases based on the cationic surfactant cetylpiridinium chloride and additives of alcohols (ethanol, 1-propanol, 1-butanol, 1-pentanol) have been obtained in this work. The effect of mobile phase properties on the motion of mobile phase in the ascending mode of thin-layer chromatography (TLC) was investigated. The applicability of a quadratic relationship between the time of mobile phase motion and the distance from the solvent entry position of mobile phase and front of the mobile phase was validated for micellar TLC. It was observed that the retardation factors of hydrophilic test compounds change significantly only at low contents of the modifier in micellar mobile phase.

引用

页码：463 / 469

页数：7

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