Intramolecular 1,3-dipolar cycloadditions of norbornadiene-tethered nitrile oxides

被引：37
|
作者：
Yip, C [1 ]
Handerson, S [1 ]
Tranmer, GK [1 ]
Tam, W [1 ]
机构：
[1] Univ Guelph, Guelph Waterloo Ctr Grad Work Chem, Dept Chem & Biochem, Guelph, ON N1G 2W1, Canada
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 01期
关键词：
D O I：
10.1021/jo005611o
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Efficient routes to the synthesis of norbornadiene-tethered nitrile oxide; have been developed, and their intramolecular 1.3-dipolar cycloadditions were studied. The cycloadditions occurred in good yields for a variety of substrates and were found to be highly regio- and stereoselective, giving single regio- and stereoisomers in most cases.
引用
收藏
页码：276 / 286
页数：11
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