Resistivity, magnetoresistance, and Mossbauer effect of metallic spiral antiferromagnet SrFeO2.95 have been examined in the temperature range 4.5-300 K. A large negative magnetoresistance below 50 K is observed. We find hysteresis in resistivity in 0 and 9 T due to the coexistence of antiferromagnetic and paramagnetic domains in the temperature region 50-80 K. Our result shows two contributions to magnetoresistance: one below 50 K that is due to helical-conical spin transformation and another close to TN that is due to reduced spin fluctuation under magnetic field.