Good Fences Make Good Neighbors: Crumbs Regulates Rho-Kinase Dynamics to Assemble a Tissue Boundary

被引：0
|
作者：
Yu-Kemp, Hui-Chia [1 ,2 ]
Peifer, Mark [1 ,2 ]
机构：
[1] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
来源：
DEVELOPMENTAL CELL | 2020年 / 52卷 / 03期
基金：
英国医学研究理事会;
关键词：
DIFFERENTIAL EXPRESSION;
D O I：
10.1016/j.devcel.2020.01.018
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Boundary formation between nascent tissues prevents cell mixing, powering morphogenesis. In this issue of Developmental Cell, Sidor et al. (2020) describe a novel mechanism whereby the homophilic adhesion protein Crumbs regulates planar-polarized assembly of actomyosin cables at tissue boundaries by affecting dynamics of membrane recruitment of the myosin regulator Rho-kinase.
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页码：255 / 256
页数：2
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