LPS induces s-nitrosation of IRβ/IRS-1 and Akt and insulin resistance in muscle of mice

被引:0
|
作者
Carvalho, MA
Ueno, M
Hirabara, SM
Seabra, AB
Carvalheira, JBC
Oliveira, MG
Velloso, LA
Curi, R
Saad, MJA
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:A59 / A59
页数:1
相关论文
共 50 条
  • [21] Insulin resistance due to phosphorylation of IRS-1 at serine 302
    Lee, J
    Werner, ED
    Hansen, L
    Yuan, MS
    Shoelson, SE
    DIABETES, 2004, 53 : A312 - A312
  • [22] O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes
    Seung Yoon Park
    Jiwon Ryu
    Wan Lee
    Experimental & Molecular Medicine, 2005, 37 : 220 - 229
  • [23] Muscle-specific IRS-1 Ser→Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle
    Morino, Katsutaro
    Neschen, Susanne
    Bilz, Stefan
    Sono, Saki
    Tsirigotis, Dimitrios
    Reznick, Richard M.
    Moore, Irene
    Nagai, Yoshio
    Samuel, Varman
    Sebastian, David
    White, Morris
    Philbrick, William
    Shulman, Gerald I.
    DIABETES, 2008, 57 (10) : 2644 - 2651
  • [24] Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
    Hoy, Andrew J.
    Brandon, Amanda E.
    Turner, Nigel
    Watt, Matthew J.
    Bruce, Clinton R.
    Cooney, Gregory J.
    Kraegen, Edward W.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2009, 297 (01): : E67 - E75
  • [25] Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRβ/IRS-1 and Akt (Publication with Expression of Concern)
    Carvalho-Filho, M. A.
    Ropelle, E. R.
    Pauli, R. J.
    Cintra, D. E.
    Tsukumo, D. M. L.
    Silveira, L. R.
    Curi, R.
    Carvalheira, J. B. C.
    Velloso, L. A.
    Saad, M. J. A.
    DIABETOLOGIA, 2009, 52 (11) : 2425 - 2434
  • [26] Atorvastatin induces profound insulin sensitization in Zucker lean rats by stimulating Akt/PKB phosphorylation independent of IRS-1
    Leung, N
    Stavar, L
    Sakaue, T
    Szeto, L
    Uffelman, K
    Adeli, K
    Fantus, G
    Lewis, G
    DIABETES, 2003, 52 : A330 - A330
  • [27] IRS-1 links insulin signaling to ion flux in muscle.
    Algenstaedt, P
    Antonetti, D
    Kahn, CR
    DIABETES, 1996, 45 : 440 - 440
  • [28] Insulin signaling and regulation of gene expression in vascular smooth muscle cells of IRS-1 knockout mice
    Jiang, ZY
    King, B
    Winnay, J
    Qu, CS
    Li, ZL
    Takahara, H
    DIABETES, 1999, 48 : A221 - A221
  • [29] O-GlcNAc modific ation on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes
    Park, SY
    Ryu, JW
    Lee, W
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2005, 37 (03): : 220 - 229
  • [30] iNOS gene disruption restores depressed IRS-1 expression in skeletal muscle and ameliorates insulin resistance in diabetic (ob/ob) mice
    Sugita, H
    Sugita, M
    Kaneki, M
    DIABETES, 2003, 52 : A295 - A295