AIE materials for lysosome imaging

被引：5
|
作者：
Gupta, Ankush [1 ]
Kumar, Manoj [2 ]
Bhalla, Vandana [2 ]
机构：
[1] DAV Univ, Dept Chem, Jalandhar, Punjab, India
[2] Guru Nanak Dev Univ, UGC Sponsored Ctr Adv Studies 2, Dept Chem, Amritsar, Punjab, India
来源：
ADVANCES IN AGGREGATION INDUCED EMISSION MATERIALS IN BIOSENSING AND IMAGING FOR BIOMEDICAL APPLICATIONS, PT A | 2021年 / 184卷
关键词：
AGGREGATION-INDUCED-EMISSION; LIGHT-UP PROBE; 2-PHOTON FLUORESCENT-PROBE; LIVE CELLS; HYDROGEN-SULFIDE; VISCOSITY; APOPTOSIS; BIOPROBE; DOTS; PHOSPHATASE;
D O I：
10.1016/bs.pmbts.2021.08.001
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The aggregation-induced emission (AIE) active bioprobes are known for their high photostability and extraordinary signal to noise ratio. In view of this, research efforts to synthesize new AIE bioimaging probes are at an incredible speed. In this chapter, we have summarized the various lysosome specific AIE active "turn-on" bioprobes having applications in lysosome imaging, monitoring of lysosome bioactivity and evaluation of their therapeutic effects. By discussing their design and operational mechanisms, we hope to provide more insight into designing new AIE bioprobes for specific sensing and imaging of lysosome having flexibility for broad range of biomedical applications.
引用
收藏
页码：145 / 178
页数：34
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