Corticosteroids do not influence the efficacy and kinetics of CAR-T cells for B-cell acute lymphoblastic leukemia

被引:116
|
作者
Liu, Shuangyou [1 ]
Deng, Biping [2 ]
Yin, Zhichao [1 ]
Pan, Jing [1 ]
Lin, Yuehui [1 ]
Ling, Zhuojun [1 ]
Wu, Tong [3 ]
Chen, Dong [1 ,4 ]
Chang, Alex H. [5 ]
Gao, Zhiyong [3 ]
Song, Yanzhi [3 ]
Zhao, Yongqiang [3 ]
Tong, Chunrong [1 ]
机构
[1] Beijing Boren Hosp, Dept Hematol, Beijing, Peoples R China
[2] Beijing Boren Hosp, Cytol Lab, Beijing, Peoples R China
[3] Beijing Boren Hosp, Dept Bone Marrow Transplantat, Beijing, Peoples R China
[4] Mayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN USA
[5] Tongji Univ, Sch Med, Shanghai Pulm Hosp, Clin Translat Res Ctr, Shanghai, Peoples R China
关键词
THERAPY;
D O I
10.1038/s41408-020-0280-y
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页数:4
相关论文
共 50 条
  • [21] Inhibiting Free Fatty Acid Transport to Improve CAR-T Cell Therapy of Relapsed B-Cell Acute Lymphoblastic Leukemia
    Garcia, Clarissa
    Lyons, Kaylyn
    Liu, Tian
    Iacobucci, Ilaria
    Novak, Amanda
    Argabright, Amy
    Donnelly, Alexis
    Contreras, Julian Grandvallet
    Geng, Huimin
    Smith, Sabrina
    Zhou, Xin
    Muschen, Markus
    Dick, John Edgar
    Haines, Julie R.
    D'Alessandro, Angelo
    Mullighan, Charles G.
    Phang, Tzu
    Kohler, Eric
    Witkowski, Matthew
    BLOOD, 2024, 144 : 1446 - 1447
  • [22] Detection, Monitoring and Cell Kinetics of Circulating CAR-T Cells in B-Cell Malignancies
    Sierro, Belen
    Beatriz Garcia-Calderon, Clara
    Sanoja-Flores, Luzalba
    Ruiz-Maldonado, Victoria
    Delgado Serrano, Javier
    Molinos-Quintana, Agueda
    Luis Reguera, Juan
    Guijarro-Albaladejo, Beatriz
    Reinoso-Segura, Marta
    Garcia-Guerrero, Estefania
    Perez-Simon, Jose A.
    Caballero, Teresa
    BLOOD, 2022, 140 : 7550 - 7551
  • [23] Use of cardiac radiation therapy as bridging therapy to CAR-T for relapsed pediatric B-cell acute lymphoblastic leukemia
    Marquez, Cesar P.
    Montiel-Esparza, Raul
    Hui, Caressa
    Schultz, Liora M.
    Davis, Kara L.
    Hoppe, Richard T.
    Donaldson, Sarah S.
    Ramakrishna, Sneha
    Hiniker, Susan M.
    PEDIATRIC BLOOD & CANCER, 2021, 68 (03)
  • [24] Multiple CAR-T cell therapy for acute B-cell lymphoblastic leukemia after hematopoietic stem cell transplantation: A case report
    Deng, Lei
    Yu, Xiaolin
    Wu, Qian
    Song, Xiaochen
    Li, Wenjun
    Hou, Yixi
    Liu, Yue
    Wang, Jing
    Tian, Jun
    Zuo, Xiaona
    Zhou, Fang
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [25] Clinical experience of CAR T cells for B cell acute lymphoblastic leukemia
    Fabrizio, Vanessa A.
    Curran, Kevin J.
    BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2021, 34 (03)
  • [26] Dual-targeting CAR T cells for B-cell acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma
    Canedo, Gustavo de Oliveira
    Roddie, Claire
    Amrolia, Persis J.
    BLOOD ADVANCES, 2025, 9 (04) : 704 - 721
  • [27] CD19-specific car-t cells for the treatment of cns chloromas in children with relapsed/refractory b-cell acute lymphoblastic leukemia
    Shahid, S.
    Cancio, M.
    Haque, S. S.
    Khakoo, Y.
    McWilliams, E.
    Santomasso, B. D.
    Scaradavou, A.
    Spitzer, B.
    Wolden, S. L.
    Boelens, J. J.
    Curran, K. J.
    BONE MARROW TRANSPLANTATION, 2022, 57 (SUPPL 1) : 137 - 138
  • [28] CAR-T treatment is safe and effective in adult patients with Down syndrome and B-cell acute lymphoblastic leukemia (B-ALL)
    Galli, Eugenio
    Corrente, Alessandro
    Chiusolo, Patrizia
    Sica, Simona
    Sora, Federica
    BONE MARROW TRANSPLANTATION, 2024, 59 (11) : 1611 - 1613
  • [29] Optimizing the Clinical Impact of CAR-T Cell Therapy in B-Cell Acute Lymphoblastic Leukemia: Looking Back While Moving Forward
    Safarzadeh Kozani, Pouya
    Safarzadeh Kozani, Pooria
    Rahbarizadeh, Fatemeh
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [30] Success of donor-derived CAR-T cells after failure of autologous CD19 CAR-T cells (tisagenlecleucel) in B-cell acute lymphoblastic leukaemia
    Dourthe, Marie Emilie
    Yakouben, Karima
    David, Audrey
    Thouvenin, Sandrine
    Chaillou, Delphine
    Caillat-Zucman, Sophie
    Cuffel, Alexis
    Tardy, Clea
    Lainey, Elodie
    Caye-Eude, Aurelie
    Arfeuille, Chloe
    Delaugerre, Constance
    Chaix-Baudier, Marie-Laure
    Naudin, Jerome
    Auvin, Stephane
    Bergaoui, Karim
    Merlat-Guitard, Anne-Isabelle
    De Jorna, Romain
    Mebarki, Miryam
    Dalle, Jean-Hugues
    Baruchel, Andre
    BRITISH JOURNAL OF HAEMATOLOGY, 2024, 205 (01) : 373 - 377