IL-6 Muscles In on the Gut and Pancreas to Enhance Insulin Secretion

被引：17
|
作者：
Allen, Tamara L. [1 ]
Whitham, Martin [1 ]
Febbraio, Mark A. [1 ]
机构：
[1] Baker IDI Heart & Diabet Inst, Cellular & Mol Metab Lab, Melbourne, Vic 3008, Australia
来源：
CELL METABOLISM | 2012年 / 15卷 / 01期
关键词：
GLUCOSE-HOMEOSTASIS; INTERLEUKIN-6; DOES/DOES; SKELETAL-MUSCLE; BENEFICIAL ROLE; SENSITIVITY; OXIDATION; EXERCISE; HUMANS;
D O I：
10.1016/j.cmet.2011.12.004
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The role of the cytokine interleukin-6 (IL-6) in metabolic homeostasis is the subject of conjecture. Recent work in Nature Medicine (Ellingsgaard et al., 2011) demonstrates that IL-6 released from skeletal muscle during exercise mediates crosstalk between insulin-sensitive tissues, intestinal L cells, and pancreatic islets to adapt to changes in insulin demand.
引用
收藏
页码：8 / 9
页数：2
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