Urinary bisphenol levels in plastic industry workers

被引：17
|
作者：
Rebai, Imene [1 ,2 ]
Fernandes, Jose O. [3 ]
Azzouz, Mohamed [4 ]
Benmohammed, Karima [2 ,5 ]
Bader, Ghania [6 ]
Benmbarek, Karima [7 ]
Cunha, Sara C. [3 ]
机构：
[1] Salah Boubnider Univ 3, Fac Med, Lab Toxicol, Constantine, Algeria
[2] Salah Boubnider Univ 3, Lab Prevent Med Chron Dis, Constantine, Algeria
[3] Univ Porto, Fac Pharm, Lab Bromatol & Hidrol, LAQV,REQUIMTE, Porto, Portugal
[4] Youcef Benkhedda Univ I, Fac Med, Lab Toxicol, Algiers, Algeria
[5] Salah Boubnider Univ 3, Fac Med, Endocrinol Dept, Constantine, Algeria
[6] Local Hlth Estab Hamma Bouziane, Occupat Med Dept, Constantine, Algeria
[7] Salah Boubnider Univ 3, Fac Med, Biochem Dept, Constantine, Algeria
来源：
ENVIRONMENTAL RESEARCH | 2021年 / 202卷
关键词：
Bisphenol A; Analogs; Occupational exposure; Urine; Men's reproductive health; Prevention; OCCUPATIONAL-EXPOSURE; A CONCENTRATIONS; PREGNANT-WOMEN; ADULTS; DETERMINANTS; POPULATION; MECHANISMS; BLOOD;
D O I：
10.1016/j.envres.2021.111666
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Bisphenol A (BPA) is a known endocrine disruptor compound that is widely applied as a monomer base in polycarbonate plastics and as a binding agent in several epoxy resins. Plastic industry workers have usually heavier and prolonged exposures to BPA. Hence, the present work aims to assess the levels of BPA and their analogs (S, F, B, AF, Z, E, and AP) in 170 urine samples from a cross-sectional study of workers from a plastic industry located in north Constantine (Algeria). This work was complemented with a questionnaire about sexual functions and evaluation of sexual hormone levels. The results showed a stable presence of BPA (average of 3.24 mu g/L), accounting for more than 90% of the total BPs. Of the remaining BP analogs, only trace amounts of BPB were detected in three samples (average of 2.73 mu g/L). Significant associations with BPA urinary levels were noted with age (p = 0.006), occupational level of exposure (p = 0.023), and years of experience (p = 0.001).
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页数：7
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