Fine-Tuning Th17 Cells: To Be or Not To Be Pathogenic?

被引：10

作者：

Kanellopoulou, Chrysi ^{[1
]}

Muljo, Stefan A. ^{[1
]}

机构：

[1] NIAID, Immunol Lab, NIH, Bldg 10, Bethesda, MD 20892 USA

来源：

IMMUNITY | 2016年 / 44卷 / 06期

关键词：

PROGRESSIVE HEARING-LOSS; T(H)17 CELLS; DIFFERENTIATION; INDUCTION; MIR-96; SGK1;

D O I：

10.1016/j.immuni.2016.06.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Like the story of Jekyll and Hyde, Th17 cells have two guises. One helps with host immunity, but the other can cause immunopathology. In this issue of Immunity, Dong and colleagues report that three microRNAs, miR183, miR-96, and miR-182, can enhance the pathogenicity of Th17 cells (Ichiyama et al., 2016).

引用

页码：1241 / 1243

页数：3

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