Phosphorylation of 2-Aryl Quinoxaline Derivatives via C-H/P-H Cross Coupling under Transition-Metal-Free Conditions

被引：1

作者：

Karimi-Nami, Rahman ^{[1
]}

Adib, Mehdi ^{[2
]}

Heydari, Forouzan ^{[2
]}

Rajai-Daryasarei, Saeideh ^{[2
]}

Karakaya, Idris ^{[3
]}

机构：

[1] Univ Maragheh, Fac Sci, Dept Chem, Maragheh, Iran

[2] Univ Tehran, Coll Sci, Sch Chem, Tehran, Iran

[3] Gebze Tech Univ, Coll Basic Sci, Dept Chem, Gebze, Turkey

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2022年 / 42卷 / 09期

关键词：

Phosphorus-substituted heterocycles; 2-Aryl quinoxalines; dialkyl phosphites; C-H activitaion; RADICAL-ADDITION; BOND FORMATION; FREE ACYLATION; PHOSPHONATION; INHIBITORS; ACCESS; ACID;

D O I：

10.1080/10406638.2021.1983619

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this study, we have developed an efficient protocol for synthesis of phosphorus-substituted heterocycles through reaction between 2-Aryl quinoxalines and dialkyl phosphites under transition-metal-free conditions. Here, K2S2O8 has been used as the sole oxidant for the facile synthesis of phosphorus substituted derivates. A variety of heteroaryl phosphonate derivatives have been synthesized under optimized conditions in good to excellent yields with this facile and environment friendly protocol.

引用

页码：6411 / 6416

页数：6

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