Differences on the Mechanism of Action between the Radiolabeled Somatostatin Receptor Antagonist 177Lu-OPS201 and the Agonist 177Lu-DOTA-TATE: an in vitro Investigation

被引：0
|
作者：
Mansi, R. [1 ]
Santoianni-Klauer, D. [1 ]
Del Pozzo, L. [1 ]
Plas, P. [2 ]
Fani, M. [1 ]
机构：
[1] Univ Basel, Univ Hosp Basel, Basel, Switzerland
[2] Inst Henri Beaufour, Ipsen, Les Ulis, France
来源：
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING | 2018年 / 45卷
关键词：
D O I：
暂无
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OP-024
引用
收藏
页码：S14 / S15
页数：2
相关论文
共 50 条
  • [21] Comparison of the Therapeutic Response to Treatment with a 177Lu-Labeled Somatostatin Receptor Agonist and Antagonist in Preclinical Models
    Dalm, Simone U.
    Nonnekens, Julie
    Doeswijk, Gabriela N.
    de Blois, Erik
    van Gent, Dik C.
    Konijnenberg, Mark W.
    de Jong, Marion
    JOURNAL OF NUCLEAR MEDICINE, 2016, 57 (02) : 260 - 265
  • [22] Dose escalation of an Evans blue-modified radiolabeled somatostatin analog 177Lu-DOTA-EB-TATE in the treatment of metastatic neuroendocrine tumors
    Liu, Qingxing
    Cheng, Yuejuan
    Zang, Jie
    Sui, Huimin
    Wang, Hao
    Jacobson, Orit
    Zhu, Zhaohui
    Chen, Xiaoyuan
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020, 47 (04) : 947 - 957
  • [23] Somatostatin-receptor avidity of pancreatic neuroendocrine tumor thrombus in porto-caval venous systems on 99mTc-Octreotide and posttherapeutic 177Lu-DOTA-TATE scans
    Amoui, Mahasti
    Ahmadi, Reyhane
    Qutbi, Mohsen
    Asli, Isa Neshandar
    WORLD JOURNAL OF NUCLEAR MEDICINE, 2021, 20 (03) : 324 - 326
  • [24] Safety, Pharmacokinetics, and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analog 177Lu-DOTA-EB-TATE in Patients with Advanced Metastatic Neuroendocrine Tumors
    Zhang, Jingjing
    Wang, Hao
    Jacobson, Orit
    Cheng, Yuejuan
    Niu, Gang
    Li, Fang
    Bai, Chunmei
    Zhu, Zhaohui
    Chen, Xiaoyuan
    JOURNAL OF NUCLEAR MEDICINE, 2018, 59 (11) : 1699 - 1705
  • [25] Evaluation of Safety, Biodistribution, and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analog 177Lu-DOTA-EB-TATE With and Without Amino Acid Infusion
    Jiang, Yuanyuan
    Liu, Qingxing
    Wang, Guochang
    Zhang, Jingjing
    Zhu, Zhaohui
    Chen, Xiaoyuan
    CLINICAL NUCLEAR MEDICINE, 2023, 48 (06) : E289 - E293
  • [26] OPS-C-001: A Phase I/II Study to Investigate Safety, Tolerability, Biodistribution, Dosimetry and Preliminary Efficacy of 177Lu-OPS201 for the Therapy of Somatostatin Receptor (SSTR)-Positive Neuroendocrine Tumours (NETs)
    Nicolas, G.
    Baum, R. P.
    Herrmann, K.
    Lassmann, M.
    Hicks, R.
    Haug, A.
    Wahba, M.
    Wang, T.
    Wild, D.
    NEUROENDOCRINOLOGY, 2019, 108 : 224 - 224
  • [27] Hormonal crises induced by receptor radionuclide therapy with the radiolabeled somatostatin analog [177Lu-DOTA0, Tyr3] octreotate
    de Keizer, B.
    Krenning, E. P.
    Kam, B. L. R.
    van Essen, M.
    de Herder, W. W.
    Feelders, R. A.
    van Aken, M. O.
    Kwekkeboom, D. J.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2007, 34 : S220 - S221
  • [28] Hormonal crises following receptor radionuclide therapy with the radiolabeled somatostatin analogue [177Lu-DOTA0,Tyr3]octreotate
    Bart de Keizer
    Maarten O. van Aken
    Richard A. Feelders
    Wouter W. de Herder
    Boen L. R. Kam
    Martijn van Essen
    Eric P. Krenning
    Dik J. Kwekkeboom
    European Journal of Nuclear Medicine and Molecular Imaging, 2008, 35 : 749 - 755
  • [29] PRE-CLINICAL EFFICACY STUDY OF INTRA-THECAL (IT) 177LU-DOTA-TATE (SOMATOSTATIN ANALOGUE) IN ATHYMIC RATS WITH LEPTOMENINGEAL DISEASE (LMD) FROM MEDULLOBLASTOMA (MBL)
    Vaidyanathan, Ganesan
    Gururangan, Sri
    Bigner, Darell
    Zalutsky, Michael
    NEURO-ONCOLOGY, 2014, 16 : 71 - 71
  • [30] Hormonal crises following receptor radionuclide therapy with the radiolabeled somatostatin analogue [177Lu-DOTA0, Tyr3]octreotate
    de Keizer, Bart
    van Aken, Maarten O.
    Feelders, Richard A.
    de Herder, Wouter W.
    Kam, Boen L. R.
    van Essen, Martijn
    Krenning, Eric P.
    Kwekkeboom, Dik J.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2008, 35 (04) : 749 - 755
12345