Cytomegalovirus-specific adoptive cellular therapy results in massive and persistent expansions of CMV-specific T-cells and significantly reduces the incidence of CMV reactivation following allogeneic transplantation.

被引：0
|
作者：
Peggs, K
Verfuerth, S
Pizzey, A
Khan, N
Moss, P
Mackinnon, S
机构：
[1] UCL Hosp, Dept Hematol, London, England
[2] CRC, Inst Canc Studies, Birmingham, W Midlands, England
来源：
BLOOD | 2001年 / 98卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
3240
引用
收藏
页码：779A / 779A
页数：1
相关论文
共 50 条
  • [41] Adoptive transfer of ex vivo streptamer-enriched CMV-specific CD8 T cells in patients after allogeneic hematopoietic stem cell transplantation - a phase I/II trial
    Neuenhahn, M.
    Grigoleit, G. U.
    Tonn, T.
    Odendahl, M.
    Germeroth, L.
    Busch, D. H.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2009, 299 : 34 - 34
  • [42] Protective Immunity Transferred by Infusion of Cytomegalovirus-Specific CD8+ T Cells within Donor Grafts: Its Associations with Cytomegalovirus Reactivation Following Unmanipulated Allogeneic Hematopoietic Stem Cell Transplantation
    Luo, Xiao-Hua
    Huang, Xiao-Jun
    Liu, Kai-Yan
    Xu, Lan-Ping
    Liu, Dai-Hong
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (07) : 994 - 1004
  • [43] Reconstitution of Cytomegalovirus Specific T Cells after Pediatric Allogeneic Stem Cell Transplantation: Results from a Pilot Study Using a Multi-Allele CMV Tetramer Group
    Koehl, U.
    Dirkwinkel, E.
    Koenig, M.
    Erben, S.
    Soerensen, J.
    Bader, P.
    Doerr, H. W.
    Preiser, W.
    Weissinger, E.
    Klingebiel, T.
    Martin, H.
    Lehrnbecher, T.
    KLINISCHE PADIATRIE, 2008, 220 (06): : 348 - 352
  • [44] Features of cytomegalovirus infection and evaluation of cytomegalovirus-specific T cells therapy in children's patients following allogeneic hematopoietic stem cell transplantation: A retrospective single-center study
    Ruan, Yongsheng
    Luo, Tingting
    Liu, Qiujun
    Liu, Xuan
    Chen, Libai
    Wen, Jianyun
    Xiao, Yuhua
    Xie, Danfeng
    He, Yuelin
    Wu, Xuedong
    Feng, Xiaoqin
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 12
  • [45] Prevention of CMV/EBV Reactivation By Double-Specific T Cells in Patients after Allogeneic Stem Cell Transplantation: Results from the Randomized Phase I/IIa Multivir-01 Study
    Gerbitz, Armin
    Gary, Regina
    Aigner, Michael
    Moosmann, Andreas
    Kremer, Anita
    Schmidt, Christoph
    Hirschbuehl, Klaus
    Drouet, Eva Wagner
    Hauptrock, Beate
    Teschner, Daniel
    Roesler, Wolf
    Spriewald, Bernd
    Tischer, Johanna
    Moi, Stephanie
    Balzer, Heidi
    Schaffer, Stefanie
    Bausenwein, Judith
    Wagner, Anja
    Schmidt, Franziska
    Brestrich, Jens
    Ullrich, Barbara
    Maas, Stefanie
    Herold, Susanne
    Strobel, Julian
    Zimmermann, Robert
    Weisbach, Volker
    Hansmann, Leo
    Cobo, Maria Fernanda Lammoglia
    Remberger, Mats
    Stelljes, Matthias
    Ayuk, Francis A.
    Zeiser, Robert
    Mackensen, Andreas
    BLOOD, 2023, 142
  • [46] Prevention of CMV/EBV reactivation by double-specific T cells in patients after allogeneic stem cell transplantation: results from the randomized phase I/IIa MULTIVIR-01 study
    Gerbitz, Armin
    Gary, Regina
    Aigner, Michael
    Moosmann, Andreas
    Kremer, Anita
    Schmid, Christoph
    Hirschbuehl, Klaus
    Wagner, Eva
    Hauptrock, Beate
    Teschner, Daniel
    Roesler, Wolf
    Spriewald, Bernd
    Tischer, Johanna
    Moi, Stephanie
    Balzer, Heidi
    Schaffer, Stefanie
    Bausenwein, Judith
    Wagner, Anja
    Schmidt, Franziska
    Brestrich, Jens
    Ullrich, Barbara
    Maas, Stefanie
    Herold, Susanne
    Strobel, Julian
    Zimmermann, Robert
    Weisbach, Volker
    Hansmann, Leo
    Lammoglia-Cobo, Fernanda
    Remberger, Mats
    Stelljes, Matthias
    Ayuk, Francis
    Zeiser, Robert
    Mackensen, Andreas
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [47] T-cell immunotherapy against CMV, EBV and ADV with multivirus-specific T-cells using short-term ex vivo adoptive T-cell transfer for viral complications after allogeneic stem cell transplantation
    Feuchtinger, T.
    Joachim, L.
    Feucht, J.
    Kayser, S.
    Lang, P.
    Handgretinger, R.
    BONE MARROW TRANSPLANTATION, 2013, 48 : S272 - S272
  • [48] Adoptive Transfer of CMV- and EBV-Specific Peptide-Stimulated T Cells after Allogeneic Stem Cell Transplantation: First Results of a Phase I/IIa Clinical Trial [Multivir-01]
    Gary, Regina
    Aigner, Michael
    Moosmann, Andreas
    Ritter, Julia
    Seitz, Volkhard
    Moi, Stephanie
    Schaffer, Stefanie
    Balzer, Heidi
    Maas, Stefanie
    Strobel, Julian
    Zimmermann, Robert
    Zingsem, Juergen
    Kremer, Anita
    Hennig, Steffen
    Hummel, Michael
    Mackensen, Andreas
    Gerbitz, Armin
    BLOOD, 2016, 128 (22)
  • [49] PERFORMANCE OF QUANTIFERON-CMV® AND WHOLE-BLOOD CD4(+)CD25(+)CD134(+) ASSAYS IN IDENTIFICATION OF HUMAN CYTOMEGALOVIRUS-SPECIFIC T-CELLS IN CHILDREN POST-HAEMATOPOIETIC STEM CELL TRANSPLANTATION
    Namasivayam, Mahila
    Zaunders, John
    Ip, Susanna
    Scott, Gillian
    Shaw, Peter
    Trahair, Toby
    O'Brien, Tracey
    Rawlinson, William
    Walls, Tony
    Kelleher, Anthony
    Ziegler, John
    INTERNAL MEDICINE JOURNAL, 2011, 41 : 12 - 12
  • [50] Adoptive transfer of CMV- and EBV-specific peptide-stimulated T cells after allogeneic stem cell transplantation: first results of a phase I/IIa clinical trial [AIT-MULTIVIR-01]
    Gary, R.
    Aigner, M.
    Moosmann, A.
    Moi, S.
    Schaffer, S.
    Balzer, H.
    Maas, S.
    Strobel, J.
    Zimmermann, R.
    Zingsem, J.
    Kremer, A.
    Meintker, L.
    Mackensen, A.
    Gerbitz, A.
    ONCOLOGY RESEARCH AND TREATMENT, 2017, 40 : 239 - 239
12345