Comparison between Quanti-FERON-TB Gold In-Tube test and tuberculin skin test for diagnosis of latent tuberculosis in children: A cross-section study

被引：0
|
作者：
Ghadiri, Keyghobad [1 ]
Akya, Alisha [1 ]
Janatolmakan, Maryam [2 ]
Rezaei, Mansour [3 ]
Sharif, Seyed Amirabbas [4 ]
Masoomshahi, Shahla [2 ]
Khosravi, Raha [5 ]
chegenelorestani, Roya [1 ]
机构：
[1] Kermanshah Univ Med Sci, Infect Dis Res Ctr, Kermanshah, Iran
[2] Kermanshah Univ Med Sci, Imam Reza Hosp, Clin Res Dev Ctr, Kermanshah, Iran
[3] Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran
[4] Kashan Univ Med Sci, Infect Dis Res Ctr, Kashan, Iran
[5] Shahid Behehsti Univ Med Sci, Res Inst Children Hlth, Mofid Children Hosp, Pediat Pathol Res Ctr, Tehran, Iran
来源：
JOURNAL OF ACUTE DISEASE | 2020年 / 9卷 / 02期
关键词：
Tuberculosis; Latent tuberculosis infection; Tuberculin skin test; Quanti FERON; GAMMA RELEASE ASSAYS; HEALTH-CARE WORKERS; MYCOBACTERIUM-TUBERCULOSIS; NOSOCOMIAL TRANSMISSION; INFECTION; EXPOSURE; RISK;
D O I：
10.4103/2221-6189.281321
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Objective: To compare Quanti-FERON-TB Gold In-Tube (QFT- GIT) test and tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection in children. Methods: In this cross-sectional study, 64 participants who were between 3 months and 14 years old and had close contact with smear-positive pulmonary tuberculosis were included. Both QFT- GIT test and TST were done and the results were analyzed by SPSS software and Kappa test. Results: The distribution of gender and age according to QFT-GIT and TST results were matched (P>0.05). Overall agreement between QFT-GIT and TST for diagnosis of latent tuberculosis infection in children was 75%. In addition, the contingency coefficient was 0.257, and the Kappa measure of agreement was 0.246 (P=0.034). Conclusions: Compared to TST, QFT-GIT shows no apparent advantage for diagnosis of latent tuberculosis infection in children.
引用
收藏
页码：73 / 77
页数：5
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