Soy protein ingestion results in less prolonged p70S6 kinase phosphorylation compared to whey protein after resistance exercise in older men

被引:33
|
作者
Mitchell, Cameron J. [1 ]
Della Gatta, Paul A. [2 ]
Petersen, Aaron C. [3 ]
Cameron-Smith, David [1 ,2 ]
Markworth, James F. [1 ,2 ]
机构
[1] Univ Auckland, Liggins Inst, Fac Med & Sci Hlth, Auckland 1023, New Zealand
[2] Deakin Univ, Sch Exercise & Nutr Sci, Ctr Phys Act & Nutr Res, Melbourne, Vic, Australia
[3] Victoria Univ, Coll Sport & Exercise Sci, Inst Sport Exercise & Act Living, Melbourne, Vic 8001, Australia
来源
JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION | 2015年 / 12卷
关键词
Anabolic signalling; Supplementation; Aging; Sarcopenia; SKELETAL-MUSCLE STRENGTH; YOUNG; MASS; ISOLATE; REST;
D O I
10.1186/s12970-015-0070-2
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: The phosphorylation of p70S6 Kinase (p70S6K) is an important step in the initiation of protein translation. p70S6K phosphorylation is enhanced with graded intakes of whey protein after resistance exercise. Soy protein ingestion results in lower muscle protein synthesis after exercise compared with whey; however, the underlying mechanisms responsible for this difference have not been reported. Findings: 13 older men (60-75) completed an acute bout of lower body resistance exercise and ingested 30 g of soy protein or carbohydrate. Muscle biopsies were obtained in the rested and fasted state and 2 and 4 hours post exercise. Phosphorylation status of p70S6K was measured with western blot. Results were compared with previously reported data from the ingestion of 30 g of whey protein or placebo. p70S6K phosphorylation was increased 2, but not 4 hours post exercise with soy protein ingestion. p70S6K phosphorylation was not increased post exercise with carbohydrate ingestion. Conclusions: Ingesting 30 g of either whey or soy protein resulted in equivalent p70S6K phosphorylation at 2 hours post exercise, however, unlike whey, soy protein failed to promote prolonged phosphorylation of p70S6K to 4 hours post-exercise.
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页数:4
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