Transcription: Gene control by targeted histone acetylation

被引：117
|
作者：
Imhof, A [1 ]
Wolffe, AP [1 ]
机构：
[1] NICHD, Mol Embryol Lab, NIH, Bethesda, MD 20892 USA
来源：
CURRENT BIOLOGY | 1998年 / 8卷 / 12期
关键词：
D O I：
10.1016/S0960-9822(98)70268-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A transcriptional regulator in yeast, Gcn5p, activates transcription by targeted acetylation of specific lysine residues in the amino-terminal tails of histones, This targeted modification is restricted to nucleosomes assembled on the promoters of Gcn5p-responsive genes.
引用
收藏
页码：R422 / R424
页数：3
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