One-Pot Synthesis Bodipy Nano-Precipitations for Prostate Cancer Treatment

被引：0
|
作者：
Wang, Jianan [1 ]
Tian, Chao [1 ]
Cao, Zhengguo [1 ]
机构：
[1] Yuebei Peoples Hosp, Dept Urol, Shaoguan 512000, Guangdong, Peoples R China
来源：
JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING | 2022年 / 12卷 / 08期
关键词：
One-Pot; Bodipy; Photodynamic Therapy; Prostate Cancer; TUMOR-TARGETED DELIVERY; OSTEOBLAST PROMOTION; CALCIUM SUPPLEMENT; NANOPARTICLES; THERAPY; ROS; ICG;
D O I：
10.1166/jbt.2022.3070
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Here in this study, we proposed a polystyrene maleic anhydride (PSMA) stabilized Bodipy nanoparticles (PB NPs) in a one-pot approach for the photodynamic therapy (PDT) of prostate cancer. The nanoparticle formed by precipitation method was then employed to treat PC-3 cells and PC-3 tumor bearing nude mice model. It was shown that this platform showed promising anticancer performance than free bodipy with reduced side effects.
引用
收藏
页码：1537 / 1541
页数：5
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