Datopotamab deruxtecan in advanced/metastatic HER2-breast cancer: Results from the phase 1 TROPION-PanTumor01 study

被引：44
|
作者：
Krop, Ian
Juric, Dejan
Shimizu, Toshio
Tolcher, Anthony
Spira, Alexander
Mukohara, Toru
Lisberg, Aaron E.
Kogawa, Takahiro
Papadopoulos, Kyriakos P.
Hamilton, Erika
Damodaran, Senthil
Greenberg, Jonathan
Gu, Wen
Kobayashi, Fumiaki
Guevara, Ferdinand
Jikoh, Takahiro
Kawasaki, Yui
Meric-Bernstam, Funda
Bardia, Aditya
机构：
来源：
CANCER RESEARCH | 2022年 / 82卷 / 04期
关键词：
D O I：
10.1158/1538-7445.SABCS21-GS1-05
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
GS1-05
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Datopotamab Deruxtecan in Advanced or Metastatic Non-Small Cell Lung Cancer With Actionable Genomic Alterations: Results From the Phase II TROPION-Lung05 Study
    Sands, Jacob
    Ahn, Myung-Ju
    Lisberg, Aaron
    Cho, Byoung Chul
    Blumenschein, George, Jr.
    Shum, Elaine
    Pons Tostivint, Elvire
    Goto, Yasushi
    Yoh, Kiyotaka
    Heist, Rebecca
    Shimizu, Junichi
    Lee, Jong-Seok
    Baas, Paul
    Planchard, David
    Perol, Maurice
    Felip, Enriqueta
    Su, Wu-Chou
    Zebger-Gong, Hong
    Lan, Lan
    Liu, Chelsea
    Howarth, Paul
    Chiaverelli, Rachel
    Paz-Ares, Luis
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (10)
  • [22] Datopotamab Deruxtecan Versus Docetaxel for Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer: The Randomized, Open-Label Phase III TROPION-Lung01 Study
    Ahn, Myung-Ju
    Tanaka, Kentaro
    Paz-Ares, Luis
    Cornelissen, Robin
    Girard, Nicolas
    Pons-Tostivint, Elvire
    Vicente Baz, David
    Sugawara, Shunichi
    Cobo, Manuel
    Perol, Maurice
    Mascaux, Celine
    Poddubskaya, Elena
    Kitazono, Satoru
    Hayashi, Hidetoshi
    Hong, Min Hee
    Felip, Enriqueta
    Hall, Richard
    Juan-Vidal, Oscar
    Brungs, Daniel
    Lu, Shun
    Garassino, Marina
    Chargualaf, Michael
    Zhang, Yong
    Howarth, Paul
    Uema, Deise
    Lisberg, Aaron
    Sands, Jacob
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (03)
  • [23] First-in-Human, Phase I Dose-Escalation and Dose-Expansion Study of Trophoblast Cell-Surface Antigen 2-Directed Antibody-Drug Conjugate Datopotamab Deruxtecan in Non-Small-Cell Lung Cancer: TROPION-PanTumor01
    Shimizu, Toshio
    Sands, Jacob
    Yoh, Kiyotaka
    Spira, Alexander
    Garon, Edward B.
    Kitazono, Satoru
    Johnson, Melissa L.
    Meric-Bernstam, Funda
    Tolcher, Anthony W.
    Yamamoto, Noboru
    Greenberg, Jon
    Kawasaki, Yui
    Zebger-Gong, Hong
    Kobayashi, Fumiaki
    Phillips, Penny
    Lisberg, Aaron E.
    Heist, Rebecca S.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (29) : 4678 - +
  • [24] Datopotamab deruxtecan (Dato-DXd) vs chemotherapy in previously-treated inoperable or metastatic hormone receptor-positive, HER2-negative (HR+/HER2-) breast cancer (BC): Primary results from the randomised phase III TROPION-Breast01 trial
    Bardia, A.
    Jhaveri, K.
    Im, S. A.
    Simon, S. Pernas
    De laurentiis, M.
    Wang, S.
    Martinez, N.
    Borges, G. Santos
    Cescon, D. W.
    Hattori, M.
    Lu, Y. S.
    Hamilton, E. P.
    Zhang, Q. Y.
    Tsurutani, J.
    Kalinsky, K.
    Xu, L.
    Denduluri, N.
    Rugo, H. S.
    Xu, B.
    Pistilli, B.
    ANNALS OF ONCOLOGY, 2023, 34 : S1264 - S1265
  • [25] Datopotamab Deruxtecan Versus Chemotherapy in Previously Treated Inoperable/Metastatic Hormone Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer: Primary Results From TROPION-Breast01
    Bardia, Aditya
    Jhaveri, Komal
    Im, Seock-Ah
    Pernas, Sonia
    De Laurentiis, Michelino
    Wang, Shusen
    Martinez Janez, Noelia
    Borges, Giuliano
    Cescon, David W.
    Hattori, Masaya
    Lu, Yen-Shen
    Hamilton, Erika
    Zhang, Qingyuan
    Tsurutani, Junji
    Kalinsky, Kevin
    Rubini Liedke, Pedro Emanuel
    Xu, Lu
    Fairhurst, Rick M.
    Khan, Sabrina
    Denduluri, Neelima
    Rugo, Hope S.
    Xu, Binghe
    Pistilli, Barbara
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (03)
  • [26] Datopotamab deruxtecan (Dato-DXd) vs docetaxel in previously treated advanced/metastatic (adv/met) non-small cell lung cancer (NSCLC): Results of the randomized phase III study TROPION-Lung01
    Ahn, M. J.
    Lisberg, A.
    Paz-Ares, L.
    Cornelissen, R.
    Girard, N.
    Pons-Tostivint, E.
    Baz, D. Vicente
    Sugawara, S.
    Dols, M. Cobo
    Perol, M.
    Mascaux, C.
    Poddubskaya, E.
    Kitazono, S.
    Hayashi, H.
    Sands, J.
    Hall, R.
    Zhang, Y.
    Zebger-Gong, H.
    Uema, D.
    Okamoto, I.
    ANNALS OF ONCOLOGY, 2023, 34 : S1305 - S1306
  • [27] Datopotamab deruxtecan (Dato-DXd) vs docetaxel in previously treated advanced/metastatic (adv/met) non-small cell lung cancer (NSCLC): Results of the randomized phase III study TROPION-Lung01
    Ahn, M-J.
    Lisberg, A. E.
    Paz-Ares, L.
    Cornelissen, R.
    Girard, N.
    Pons-Tostivint, E.
    Vicente Baz, D.
    Sugawara, S.
    Cobo Dols, M.
    Perol, M.
    Mascaux, C.
    Poddubskaya, E.
    Kitazono, S.
    Hayashi, H.
    Sands, J.
    Hall, R.
    Zhang, Y.
    Zebger-Gong, H.
    Uema, D.
    Okamoto, I.
    ANNALS OF ONCOLOGY, 2023, 34 : S1665 - S1666
  • [28] Datopotamab deruxtecan (Dato-DXd) vs docetaxel in previously treated advanced/metastatic (adv/met) non-small cell lung cancer (NSCLC): Results of the randomized phase III study TROPION-Lung01
    Atmaca, Akin
    Ahn, Myung-Ju
    Lisberg, Aaron
    Paz-Ares, Luis
    Cornelissen, Robin
    Girard, Nicolas
    Pons-Tostivint, Elvire
    Baz, David Vicente
    Sugawara, Shunichi
    Cobo, Manuel Angel
    Perol, Maurice
    Mascaux, Celine
    Poddubskaya, Elena
    Kitazono, Satoru
    Hayashi, Hidetoshi
    Sands, Jacob
    Hall, Richard
    Zhang, Yong
    Zebger-Gong, Hong
    Uema, Deise
    Okamoto, Isamu
    Reinmuth, Niels
    ONCOLOGY RESEARCH AND TREATMENT, 2024, 47 : 245 - 245
  • [29] Updated results from DESTINY-breast01, a phase 2 trial of trastuzumab deruxtecan (T-DXd) in HER2 positive metastatic breast cancer
    Modi, Shanu
    Saura, Cristina
    Yamashita, Toshinari
    Park, Yeon Hee
    Kim, Sung-Bae
    Tamura, Kenji
    Andre, Fabrice
    Iwata, Hiroji
    Ito, Yoshinori
    Tsurutani, Junji
    Sohn, Joohyuk
    Denduluri, Neelima
    Perrin, Christophe
    Aogi, Kenjiro
    Tokunaga, Eriko
    Im, Seock-Ah
    Lee, Keun Seok
    Hurvitz, Sara A.
    Cortes, Javier
    Lee, Caleb
    Liu, Yali
    Zhang, Lin
    Shahidi, Javad
    Yver, Antoine
    Baselga, Jose
    Krop, Ian E.
    CANCER RESEARCH, 2021, 81 (04)
  • [30] A Phase 2 Study of Datopotamab Deruxtecan (Dato-DXd) in Advanced NSCLC With Actionable Genomic Alterations (TROPION-Lung05)
    Johnson, M.
    Spira, A.
    Yoh, K.
    Heist, R.
    Lisberg, A.
    Greenberg, J.
    Phillips, P.
    Guevara, F.
    Gu, W.
    Zhang, Y.
    Sands, J.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S1098 - S1098
12345