The Victor C plus plus library for protein representation and advanced manipulation

被引:4
|
作者
Hirsh, Layla [1 ,2 ]
Piovesan, Damiano [1 ]
Giollo, Manuel [1 ,3 ]
Ferrari, Carlo [3 ]
Tosatto, Silvio C. E. [1 ]
机构
[1] Univ Padua, Dept Biomed Sci, I-35131 Padua, Italy
[2] Pontificia Univ Catolica Peru, Dept Engn, Lima, Peru
[3] Univ Padua, Dept Informat Engn, I-35121 Padua, Italy
关键词
COMPUTATIONAL STRUCTURAL BIOLOGY; STRUCTURE PREDICTION; SEQUENCE ALIGNMENTS; SECONDARY STRUCTURE; FRAMEWORK; MODEL; CASP;
D O I
10.1093/bioinformatics/btu773
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: Protein sequence and structure representation and manipulation require dedicated software libraries to support methods of increasing complexity. Here, we describe the VIrtual Constrution TOol for pRoteins (Victor) C++ library, an open source platform dedicated to enabling inexperienced users to develop advanced tools and gathering contributions from the community. The provided application examples cover statistical energy potentials, profile-profile sequence alignments and ab initio loop modeling. Victor was used over the last 15 years in several publications and optimized for efficiency. It is provided as a GitHub repository with source files and unit tests, plus extensive online documentation, including a Wiki with help files and tutorials, examples and Doxygen documentation.
引用
收藏
页码:1138 / 1140
页数:3
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