A new sesquiterpene isolated from Lindera aggregata (Sims) Kosterm.

被引:23
|
作者
Cheng, Xian-Long [1 ]
Ma, Shuang-Cheng [1 ]
Wei, Feng [1 ]
Wang, Gang-Li [1 ]
Xiao, Xin-Yue [1 ]
Lin, Rui-Chao [1 ]
机构
[1] Natl Inst Control Pharmaceut & Biol Prod, Dept Chinese Mat Med & Nat Prod, Beijing 100050, Peoples R China
关键词
lindera aggregate; Lauraceae; sesquiterpene; neolindenenonelactone;
D O I
10.1248/cpb.55.1390
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new sesquiterpene, neolindenenonelactone (1), was first isolated from the dried roots of Lindera aggregata (SIMS) KOSTERM., along with four known compounds, linderane (2), isolinderalactone (3), linderalactone (4), and 8-hydroxylindestenolide (5). Their chemical structures were elucidated using spectral analysis of fast atom bombardment mass spectroscopy, one-dimensional nuclear magnetic resonance spectroscopy and two-dimensional-nuclear magnetic resonance spectroscopy including H-1-NMR, C-13-NMR, distortionless enhancement by polarization transfer, heteronuclear multiple-bond coherence, and single-crystal X-ray diffraction techniques.
引用
收藏
页码:1390 / 1392
页数:3
相关论文
共 50 条
  • [21] A New Sesquiterpene from the Roots of Lindera strychnifolia
    Jian Bei LI1
    ChineseChemicalLetters, 2002, (10) : 965 - 967
  • [22] A new sesquiterpene from the roots of Lindera strychnifolia
    Li, JB
    Ding, Y
    Li, WM
    CHINESE CHEMICAL LETTERS, 2002, 13 (10) : 965 - 967
  • [23] Quercetin-3-O--L-rhamnopyranoside derived from the leaves of Lindera aggregata (Sims) Kosterm. evokes the autophagy-induced nuclear factor erythroid 2-related factor 2 antioxidant pathway in human umbilical vein endothelial cells
    Han, Haote
    Xu, Bo
    Amin, Awais
    Li, Hongliang
    Yu, Xiuying
    Gong, Minghua
    Zhang, Lin
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 43 (01) : 461 - 474
  • [24] Cytotoxic and Antimicrobial Compounds from Cinnamomum cebuense Kosterm. (Lauraceae)
    Espineli, Dinah L.
    Agoo, Esperanza Maribel G.
    del Fierro, Ramon S.
    Shen, Chien-Chang
    Ragasa, Consolacion Y.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2014, 48 (09) : 598 - 602
  • [25] Sesquiterpenoids from the Root Tubers of Lindera aggregata
    Qiang, Yin
    Yang, Zhong-Duo
    Yang, Jun-Li
    Gao, Kun
    PLANTA MEDICA, 2011, 77 (14) : 1610 - 1616
  • [26] A novel bisbenzylisoquinoline alkaloid from Lindera aggregata
    Gan, Lishe
    Zhao, Xia
    Yao, Wei
    Wu, Limao
    Li, Lianda
    Zhou, Changxin
    JOURNAL OF CHEMICAL RESEARCH, 2008, (05) : 285 - 286
  • [27] Norisoboldine, a Natural Alkaloid from Lindera aggregata (Sims) Kosterm, Promotes Osteogenic Differentiation via S6K1 Signaling Pathway and Prevents Bone Loss in OVX Mice
    Li, Shiming
    Yan, Wenliang
    Sun, Kainong
    Miao, Jingyuan
    Liu, Zichao
    Xu, Jiayang
    Wang, Xiaoyu
    Li, Bo
    Zhang, Qian
    MOLECULAR NUTRITION & FOOD RESEARCH, 2024, 68 (12)
  • [28] Cytotoxic and Antimicrobial Compounds from Cinnamomum cebuense Kosterm. (Lauraceae)
    Dinah L. Espineli
    Esperanza Maribel G. Agoo
    Ramon S. del Fierro
    Chien-Chang Shen
    Consolacion Y. Ragasa
    Pharmaceutical Chemistry Journal, 2014, 48 : 598 - 602
  • [29] Anti-inflammatory principles from Lindera aggregata
    Kuo, Ping-Chung
    Wu, Yi-Hung
    Hung, Hsin-Yi
    Lam, Sio-Hong
    Ma, Guo-Hao
    Kuo, Liang-Mou
    Hwang, Tsong-Long
    Kuo, Daih-Huang
    Wu, Tian-Shung
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 30 (13)
  • [30] Aggreganoid G, a New Methylene-Bridged Sesquiterpenoid Dimer from Lindera aggregata
    Wen, Songsong
    Wang, Weijian
    Liu, Yongjun
    Niu, Chong
    Guo, Na
    Zhu, Riran
    Xu, Yuwen
    CHEMISTRY OF NATURAL COMPOUNDS, 2024, 60 (01) : 72 - 74