Isolation, Structure Elucidation, and Biological Activity of a New Alkaloid from Zanthoxylum rhetsa

被引：0
|
作者：
Krohn, Karsten [1 ]
Cludius-Brandt, Stephan [1 ]
Schulz, Barbara [2 ]
Sreelekha, Mambatta [3 ]
Shafi, Pottachola Mohamed [3 ]
机构：
[1] Univ Paderborn, Dept Chem, D-33098 Paderborn, Germany
[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Microbiol, D-38106 Braunschweig, Germany
[3] Univ Calicut, Dept Chem, Calicut 673635, Kerala, India
来源：
NATURAL PRODUCT COMMUNICATIONS | 2011年 / 6卷 / 11期
关键词：
Zanthoxylum rhetsa; alkaloids; biological activity; ROOT BARK; CONSTITUENTS;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Several biologically active alkaloids (1-4, 6), including, a new quinazoline-6-carboxylic acid (1), were isolated from the medicinal plant Zanthoxylum rhetsa, an evergreen tree, native to subtropical areas. Whereas the pharmacological properties of the plant extract and single constituents have been widely tested, we now show that all of the metabolites have antialgal activities, all but 6 are antibacterial, and 6 and the reduction product 5 (derived from 4) are also antifungal.
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收藏
页码：1595 / 1596
页数：2
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