Endocrine paraneoplastic syndromes in small cell lung carcinoma. Two case reports

被引：0
|
作者：
Radulescu, D. [1 ]
Pripon, S. [1 ]
Bunea, D. [1 ]
Ciuleanu, T. E. [2 ]
Radulescu, L. I. [2 ]
机构：
[1] Univ Med & Pharm Iuliu Hatieganu, Med Clin 5, Cluj Napoca 3400, Romania
[2] Canc Inst Prof Dr I Chiricuta, Cluj Napoca 3400, Romania
来源：
JOURNAL OF BUON | 2007年 / 12卷 / 03期
关键词：
atrial natriuretic peptide; ectopic PTH secretion; hypercalcemia; hyponatremia; small cell lung cancer;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Paraneoplastic syndromes are frequently detected in many small cell lung cancer (SCLC) patients. In the present paper we report 2 cases of Patients diagnosed with SCLC, in whom 2 distinct endocrine paraneoplastic syndromes were identified during diagnosis. In the first patient, severe hyponatremia and renal sodium loss with inappropriate antidiuresis was found during routine laboratory tests. Serum antidiuretic hormone (ADH) level was within normal limits, but the atrial natriuretic peptide (ANP) level was elevated. The second case presented with severe hypercalcemia secondary to an excessive parathormone (PTH) secretion. We discuss the 2 cases and review the literature.
引用
收藏
页码：411 / 414
页数：4
相关论文
共 50 条
  • [21] Hyperamylasaemia and dual paraneoplastic syndromes in small cell lung cancer
    Akinosoglou, Karolina
    Siagris, Dimitrios
    Geropoulou, Eleni
    Kosmopoulou, Oliana
    Velissaris, Dimitrios
    Kyriazopoulou, Venetsana
    Gogos, Charalambos
    ANNALS OF CLINICAL BIOCHEMISTRY, 2014, 51 (01) : 101 - 105
  • [22] Small cell lung cancer associated with multiple paraneoplastic syndromes
    Franco, Diana L.
    Thomas, Leslie
    BIOMEDICA, 2017, 37 (01): : 8 - 10
  • [23] Uncommon presentations of some common malignancies - Case 1. Sequential paraneoplastic endocrine syndromes in small-cell lung cancer
    Mayer, S
    Cypess, AM
    Kocher, ON
    Berman, SM
    Huberman, MS
    Hartzband, PI
    Halmos, B
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (06) : 1312 - 1314
  • [24] Complicated paraneoplastic neurological syndromes: a report of two patients with small cell or non-small cell lung cancer
    Hiasa, Y
    Kunishige, M
    Mitsui, T
    Kondo, S
    Kuriwaka, R
    Shigekiyo, S
    Kanematsu, T
    Satake, N
    Bando, Y
    Kondo, A
    Endo, I
    Oshima, Y
    Matsumoto, T
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2003, 106 (01) : 47 - 49
  • [25] Tripe palms with oligoarthritis, two rare paraneoplastic syndromes heralding a small cell lung cancer
    Khaled, A.
    Ben Abdallah, M.
    Tekaya, R.
    Kharfi, M.
    Yahia, C. Belhadj
    Zouari, R.
    Kamoun, M. R.
    JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2009, 23 (05) : 579 - 580
  • [26] paraneoplastic neurologic disorders in small cell lung carcinoma
    Gozzard, Paul
    Woodhall, Mark
    Chapman, Caroline
    Nibber, Anjan
    Waters, Patrick
    Vincent, Angela
    Lang, Bethan
    Maddison, Paul
    NEUROLOGY, 2015, 85 (03) : 235 - 239
  • [27] Paraneoplastic opsoclonus associated with small cell lung carcinoma
    Dropcho, EJ
    NEUROLOGY, 2002, 58 (07) : A46 - A47
  • [28] Paraneoplastic Syndromes in Renal Cell Carcinoma
    Izol, Volkan
    Kaplan, Eyup
    UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY, 2014, 13 (03): : 130 - 134
  • [29] Colorectal adenosquamous and squamous cell carcinoma. Case reports
    Staniceanu, F.
    Tebeica, T.
    Tudorica, Catalina L.
    Zurac, S. A.
    Micu, V. G.
    Tudose, I
    Slavnea, Mariana A.
    Croitoru, A.
    VIRCHOWS ARCHIV, 2009, 455 : 206 - 207
  • [30] An Unusual Case of Two Paraneoplastic Neurological Syndromes in a Patient With Lung Cancer
    Pia, Shermila
    Looi, David
    Stone, Robert
    Zhong, Ning
    Lui, Forshing
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (12)
12345