Endocrine paraneoplastic syndromes in small cell lung carcinoma. Two case reports

被引：0
|
作者：
Radulescu, D. [1 ]
Pripon, S. [1 ]
Bunea, D. [1 ]
Ciuleanu, T. E. [2 ]
Radulescu, L. I. [2 ]
机构：
[1] Univ Med & Pharm Iuliu Hatieganu, Med Clin 5, Cluj Napoca 3400, Romania
[2] Canc Inst Prof Dr I Chiricuta, Cluj Napoca 3400, Romania
来源：
JOURNAL OF BUON | 2007年 / 12卷 / 03期
关键词：
atrial natriuretic peptide; ectopic PTH secretion; hypercalcemia; hyponatremia; small cell lung cancer;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Paraneoplastic syndromes are frequently detected in many small cell lung cancer (SCLC) patients. In the present paper we report 2 cases of Patients diagnosed with SCLC, in whom 2 distinct endocrine paraneoplastic syndromes were identified during diagnosis. In the first patient, severe hyponatremia and renal sodium loss with inappropriate antidiuresis was found during routine laboratory tests. Serum antidiuretic hormone (ADH) level was within normal limits, but the atrial natriuretic peptide (ANP) level was elevated. The second case presented with severe hypercalcemia secondary to an excessive parathormone (PTH) secretion. We discuss the 2 cases and review the literature.
引用
收藏
页码：411 / 414
页数：4
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