Effect of anaesthetic premedication with medetomidine-buprenorphine on the aqueous tear production in dogs

被引:6
|
作者
Soontornvipart, K
Rauser, P
Kecová, H
Lexmaulová, L
机构
[1] Chulalongkorn Univ, Fac Vet Sci, Dept Surg, Ophthalmol Clin, Bangkok 10330, Thailand
[2] Univ Vet & Pharmaceut Sci, Dept Surg & Orthopaed, Small Animn Clin, Brno, Czech Republic
关键词
Schirmer tear test; a(2)-adrenergic agonist; opioid; sedation;
D O I
10.2754/avb200372020267
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The Schirmer tear test (STT) was performed in 28 healthy dogs and five dogs with dry-eye syndrome before anaesthesia and 10 and 30 minutes after anaesthetic premedication with medetomidine (20 mug/kg) and buprenorphine (10 mug/kg). All healthy dogs had normal preanaesthetic STT values (16.9 +/- 1.08 mm/min). STT values 10 minutes after premedication were highly significantly decreased (p < 0.01) from the normal values to critical value (1.7 +/- 0.94 mm/min) and after 30 min STT was undetectable (STT 0 mm/min.). Dogs with dry-eye syndrome had preanaesthetic STT 6.4 +/- 0.18 mm/min. In comparison with healthy dogs, in this group STT values were undetectable (STT 0) already 10 min after premedication (p < 0.01). The age, breed, sex and body weight of the patients did not significantly influence the STT results. Medetomidine (20 mug/kg) with buprenorphine (10 mug/kg) is a good anaesthetic premedication that induces profound sedation and analgesia. STT was recommended as a part of preanaesthetic examination, and eye protection should be performed in each dog premedicated with medetomidine-buprenorphine to prevent corneal damage.
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页码:267 / 272
页数:6
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