Synthesis and reactivity of 4-, 5- and 6-azaindoles

被引:91
|
作者
Popowycz, Florence [1 ]
Merour, Jean-Yves [2 ]
Joseph, Benoit [1 ]
机构
[1] Univ Lyon 1, CNRS, Inst Chim Biochim Mol Supramol, Chim Organ Lab UMR 5246, F-69622 Villeurbanne, France
[2] Univ Orleans, CNRS, Inst Chim Organ Anal, UMR 6005, F-45067 Orleans, France
关键词
PALLADIUM-CATALYZED HETEROANNULATION; NONNUCLEOSIDE INHIBITORS; ANTIBACTERIAL ACTIVITY; REVERSE-TRANSCRIPTASE; EFFICIENT SYNTHESIS; DIRECT ANNULATION; FACTOR XA; DERIVATIVES; AZAINDOLES; RECEPTOR;
D O I
10.1016/j.tet.2007.05.078
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:8689 / 8707
页数:19
相关论文
共 50 条
  • [21] The Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles
    Roy, PJ
    Dufresne, C
    Lachance, N
    Leclerc, JP
    Boisvert, M
    Wang, ZY
    Leblanc, Y
    SYNTHESIS-STUTTGART, 2005, (16): : 2751 - 2757
  • [22] Regioselective halogenation of 6-azaindoles: Efficient synthesis of 3-halo-2,3-disubstituted-6-azaindole derivatives
    Gallou, F
    Reeves, JT
    Tan, ZL
    Songa, JHJ
    Yee, NK
    Campbell, S
    Jones, PJ
    Senanayake, CH
    SYNLETT, 2005, (15) : 2400 - 2402
  • [23] Synthesis and NMR study of 1-, 4-, 5- and 6-fluoroazulenes
    Le, VP
    Wells, PR
    AUSTRALIAN JOURNAL OF CHEMISTRY, 1997, 50 (12) : 1119 - 1122
  • [24] Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles
    Lougiakis, Nikolaos
    Sakalis, Nikolaos
    Georgiou, Maria
    Marakos, Panagiotis
    Pouli, Nicole
    Skaltsounis, Alexios-Leandros
    Mavrogonatou, Eleni
    Pratsinis, Harris
    Kletsas, Dimitris
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 261
  • [25] Synthesis of 2,5-Disubstituted 6-Azaindoles from Substituted Aziridines via Intramolecular Cyclization
    Lee, Hogyu
    Kim, Jun Hee
    Lee, Won Koo
    Jung, Jae-Hoon
    Ha, Hyun-Joon
    ORGANIC LETTERS, 2012, 14 (12) : 3120 - 3122
  • [26] Synthesis of Substituted 4-, 5-, 6-, and 7-Azaindoles from Aminopyridines via a Cascade C-N Cross-Coupling/Heck Reaction
    Pires, Marina J. D.
    Poeira, Diogo L.
    Purificacao, Sara I.
    Marques, M. Manuel B.
    ORGANIC LETTERS, 2016, 18 (13) : 3250 - 3253
  • [27] Synthesis of 6-azaindoles via formal electrophilic [4+1]-cyclization of 3-amino-4-methyl pyridines: new frontiers of diversity
    Ivonin, Sergey P.
    Voloshchuk, Volodymyr V.
    Rusanov, Eduard B.
    Suikov, Sergiy
    Ryabukhin, Serhiy V.
    Volochnyuk, Dmytro M.
    ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (07): : 2088 - 2094
  • [28] Synthesis of Naphthoxazoles by Photocyclization of 4-/5-(Phenylethenyl)oxazoles
    Sagud, Ivana
    Sindler-Kulyk, Marija
    Skoric, Irena
    Kelava, Vanja
    Marinic, Zeljko
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 2018 (25) : 3326 - 3335
  • [29] A novel one-step synthesis of 2-substituted 6-azaindoles from 3-amino-4-picoline and carboxylic esters
    Song, JJ
    Tan, ZL
    Gallou, F
    Xu, JH
    Yee, NK
    Senanayake, CH
    JOURNAL OF ORGANIC CHEMISTRY, 2005, 70 (16): : 6512 - 6514
  • [30] Imidazo[4,5-c]pyrazoles synthesis of 4-,5- and 6-substituted derivatives
    Vicentini, CB
    Veronese, AC
    Manfrini, M
    Guarneri, M
    TETRAHEDRON, 1996, 52 (20) : 7179 - 7182