Three-component domino [3+2] heterocyclization leading to pyran-3-yl-substituted fused pyrroles

被引：7

作者：

Wang, Shuang-Shuang ^{[1
]}

Zhu, Qi-Wei ^{[1
]}

Liu, Shuai ^{[1
]}

Yang, Yang ^{[1
]}

Wang, Zhi-Tong ^{[1
]}

Jiang, Bo ^{[1
]}

Tu, Shu-Jiang ^{[1
]}

机构：

[1] Jiangsu Normal Univ, Sch Chem & Chem Engn, Xuzhou 221116, Peoples R China

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2015年 / 41卷 / 05期

关键词：

Heterocyclization; Microwave irradiation; Fused pyrroles; Multicomponent reactions; 1,3-DIPOLAR CYCLOADDITION REACTIONS; EFFICIENT SYNTHESIS; MULTICOMPONENT REACTIONS; DERIVATIVES; HETEROANNULATION; CHEMISTRY; BIOLOGY;

D O I：

10.1007/s11164-013-1396-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Concise and efficient three-component domino [3+2] heterocyclization to pyran-3-yl-substituted fused pyrroles promoted by HOAc have been developed under microwave irradiation. The reactions showed broad scopes of substrates which can employ a wide range of readily available arylglyoxal monohydrate and N-aryl enaminones. The structures of products 4 have been unambiguously determined by NMR and HRMS analyses. The single crystal of 4a was further confirmed by X-ray diffraction analysis.

引用

页码：2879 / 2889

页数：11

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