Long-Term Outcome of Adalimumab in a Young Girl with Hidradenitis Suppurativa

被引:7
|
作者
Oranges, Teresa [1 ,2 ]
Chiricozzi, Andrea [1 ]
Iannone, Michela [1 ]
Romanelli, Marco [1 ]
Dini, Valentina [1 ]
机构
[1] Univ Pisa, Dept Dermatol, Via Roma 67, IT-56126 Pisa, Italy
[2] Univ Florence, Anna Meyer Childrens Univ Hosp, Dept Hlth Sci, Florence, Italy
来源
SKIN APPENDAGE DISORDERS | 2019年 / 5卷 / 01期
关键词
Hidradenitis suppurativa; Acne inversa; Children; Adalimumab;
D O I
10.1159/000487365
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Hidradenitis suppurativa (HS) is a chronic, burdensome inflammatory skin disorder mainly affecting adults with an infrequent onset during childhood or adolescence. Guidelines regarding the therapeutic drugs in pediatric HS patients are lacking. We describe the case of a 16-year-old girl affected by HS with a massive impact of the disease on her daily activities. She underwent antibiotics, estroprogestinics, isotretinoin, and drainage procedures with partial and short-term improvement. We treated the patient with adalimumab and assessed disease severity using BMI, pain VAS, Hurley, m-Sartorius, and HS-PGA. The treatment has been continued for 4 years with a strong improvement of clinical and psychological outcome. No side effects were recorded throughout the treatment period.
引用
收藏
页码:38 / 41
页数:4
相关论文
共 50 条
  • [11] Adalimumab for Hidradenitis Suppurativa
    No, Daniel J.
    Amin, Mina
    Wu, Jashin J.
    CUTIS, 2017, 100 (02): : 100 - 100
  • [12] Long-term risk of death in patients with hidradenitis suppurativa
    Kohorst, John J.
    Ghanavatian, Shirin
    Davis, Mark D. P.
    Weaver, Amy L.
    Schleck, Cathy D.
    Swanson, David L.
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 2023, 62 (05) : 631 - 636
  • [13] Long-term drug survival of adalimumab, infliximab, secukinumab and ustekinumab in hidradenitis suppurativa: a Danish nationwide cohort study
    Ring, Hans Christian
    Thorsen, Jonathan
    Kirby, Brian
    Ingram, John R.
    Roseno, Nana Aviaaja Lippert
    Holgersen, Nikolaj
    Nielsen, Valdemar W.
    Aagaard, David Nikolai Thein
    Maul, Julia-Tatjana
    Wu, Jashin J.
    Thyssen, Jacob P.
    Egeberg, Alexander
    Thomsen, Simon F.
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 190 (05) : 769 - 771
  • [14] Long-term adalimumab treatment of hidradenitis suppurativa: Results and practical insights from a real-life experience
    Bettoli, V.
    Manfredini, M.
    Calamo, G.
    Forconi, R.
    Bencivelli, D.
    Mantovani, L.
    Pellacani, G.
    Corazza, M.
    DERMATOLOGIC THERAPY, 2018, 31 (06)
  • [15] Adalimumab: A Review in Hidradenitis Suppurativa
    Kim, Esther S.
    Garnock-Jones, Karly P.
    Keam, Susan J.
    AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2016, 17 (05) : 545 - 552
  • [16] Treating Hidradenitis Suppurativa With Adalimumab
    Shumeyko, Emma P.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2016, 100 (05) : 404 - 404
  • [17] HUMIRA® (adalimumab) for Hidradenitis Suppurativa
    不详
    JOURNAL OF DRUGS IN DERMATOLOGY, 2012, 11 (05) : 669 - 669
  • [18] Adalimumab: A Review in Hidradenitis Suppurativa
    Esther S. Kim
    Karly P. Garnock-Jones
    Susan J. Keam
    American Journal of Clinical Dermatology, 2016, 17 : 545 - 552
  • [19] Long-term therapy with anakinra in hidradenitis suppurativa in three patients
    Andre, Raphael
    Marescassier, Helene
    Gabay, Cem
    Pittet, Brigitte
    Laffitte, Emmanuel
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 2019, 58 (11) : E208 - E209
  • [20] Long-term efficacy of a single course of infliximab in hidradenitis suppurativa
    Mekkes, J. R.
    Bos, J. D.
    BRITISH JOURNAL OF DERMATOLOGY, 2008, 158 (02) : 370 - 374