The bromoquinone annulation reaction: a formal total synthesis of EO9

被引：12
|
作者：
Comer, E [1 ]
Murphy, WS [1 ]
机构：
[1] Natl Univ Ireland Univ Coll Cork, Dept Chem, Cork, Ireland
来源：
ARKIVOC | 2003年
关键词：
EO9; synthesis; bromoquinone annulation; regiospecific;
D O I：
10.3998/ark.5550190.0004.724
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The following report describes a one-pot regiospecific annulation reaction in the production of a highly advanced EO9 precursor. This intermediate is modified in what constitutes the shortest total synthesis of the EO9 antitumor drug.
引用
收藏
页码：286 / 296
页数：11
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