Drug treatments alternative to antipsychotics in dementia patients with behavioral disturbances

被引：0

作者：

Drach, Lutz M. ^{[1
]}

Adler, Georg ^{[2
]}

机构：

[1] HELIOS Kliniken Schwerin, Carl Friedrich Flemming Klin, Klin Alterspsychiat, D-19049 Schwerin, Germany

[2] ISPG, D-68165 Mannheim, Germany

来源：

PSYCHOPHARMAKOTHERAPIE | 2010年 / 17卷 / 06期

关键词：

Dementia; non-cognitive symptoms; cholinesterase inhibitors; memantine; SSRI; trazodone; anticonvulsants; tiapride; SEVERE ALZHEIMERS-DISEASE; PLACEBO-CONTROLLED TRIAL; LEWY BODIES; FRONTOTEMPORAL DEMENTIA; DOUBLE-BLIND; OPEN-LABEL; CHOLINESTERASE-INHIBITORS; PSYCHOLOGICAL SYMPTOMS; MEMANTINE TREATMENT; VASCULAR DEMENTIA;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Treatment of non-cognitive symptoms in dementia patients with antipsychotics is associated with considerable side effects and risks. Alternative treatment options are available, particularly cholinesterase inhibitors, memantine, selective serotinin inhibitors (SSRI), monoamine oxidase (MAO) inhibitors, trazodone, tiapride and various anticonvulsants. Indications, efficacy, and side effects for these drugs in the treatment of behavioral disturbances in dementia patients are presented. The choice of drug treatment driven by target symptoms and tolerability considerations is exemplified through a case history.

引用

页码：264 / +

页数：10

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