Generation of reactive oxygen species from hinokitiol under near-UV irradiation

被引：7

作者：

Shibata, H ^{[1
]}

Nagamine, T ^{[1
]}

Wang, Y ^{[1
]}

Ishikawa, T ^{[1
]}

Sawa, Y ^{[1
]}

机构：

[1] Shimane Univ, Dept Life Sci & Biotechnol, Fac Life & Environm Sci, Matsue, Shimane 6908504, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2003年 / 67卷 / 09期

关键词：

bactericidal activity; hinokitiol; near UV; reactive oxygen species;

D O I：

10.1271/bbb.67.1996

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Near-UV irradiation caused the decomposition of hinokitiol in an aqueous solution. During the photochemical reaction, the distinct electron spin resonance signal characteristic of the adduct of 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) with the hydroxyl radical was accompanied by small signals corresponding to the adduct of DMPO with the superoxide anion radical. More than 95% of Escherichia coli cells were killed by the incubation with hinokitiol under near-UV irradiation by BLB fluorescent lamps. These results indicated the generation of reactive oxygen species during photochemical reaction of hinokitiol under near-UV irradiation.

引用

页码：1996 / 1998

页数：3

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