Total synthesis of the proposed azaspiracid-1 structure, part 1: Construction of the enantiomerically pure C1-C20, C21-C27, and C28-C40 fragments

被引:75
|
作者
Nicolaou, KC
Li, YW
Uesaka, N
Koftis, TV
Vyskocil, S
Ling, TT
Govindasamy, M
Qian, W
Bernal, F
Chen, DYK
机构
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
[3] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
关键词
asymmetric synthesis; azaspiracid-1; natural products; neurotoxins; structural revision; total synthesis;
D O I
10.1002/anie.200351825
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:3643 / 3648
页数:6
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