Restriction of sympathetic denervation during spinal anesthesia may minimize hemodynamic alterations. Theoretically, the use of nonisobaric anesthetics may allow unilateral anesthesia and thus restrict sympathetic denervation to one side of the body. The present prospective study investigates the incidence of unilateral spinal anesthesia using hyperbaric bupivacaine 0.5% (1.4 mt, 1.6 mt, 1.8 mt, or 2.0 mt) injected via a 29-gauge Quincke needle with a pump-controled injection flow of 1 mL/min. In 96 consecutive patients undergoing unilateral surgery of the lower extremities, spinal anesthesia was performed in the lateral decubitus position, which was maintained for 20 min postinjection. Increases in foot temperature of at least 0.5 degrees C were defined as sympathetic blockade. The incidence of unilateral block was not significantly influenced by the amount of bupivacaine. For all 96 patients, the incidence of unilateral sympathetic and complete motor block was 69% and 77%, respectively, Frequency of unilateral sensory block (assessed by pinprick and temperature discrimination) was significantly lower (28%). Strict unilateral spinal anesthesia was achieved in 24 cases (25%). Twenty minutes after injection of the local anesthetic, mean arterial blood pressure decreased significantly in patients with bilateral sympathetic blockade from 87 +/- 8 to 83 +/- 8 mm Hg (P < 0.01) but not in patients with unilateral sympathetic blockade (from 87 +/- 11 to 85 +/- 10 mm Hg). In conclusion, low-flow injection (1 mL/min) of hyperbaric bupivacaine 0.5% via a 29-gauge Quincke needle prevented bilateral sympathetic blockade in more than 69% of the patients. The data further suggest that loss of temperature discrimination alone is not a reliable estimation of sympathetic block.
机构:
Childrens Welf Teaching Hosp, Dept Pediat & Neonatal Anesthesia, Med City, Baghdad, IraqChildrens Welf Teaching Hosp, Dept Pediat & Neonatal Anesthesia, Med City, Baghdad, Iraq
Hamed, Riyadh Khudeir
Hartmans, Sharon
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机构:
Harbor UCLA Med Ctr, Dept Med, Torrance, CA 90509 USAChildrens Welf Teaching Hosp, Dept Pediat & Neonatal Anesthesia, Med City, Baghdad, Iraq
Hartmans, Sharon
Gausche-Hill, Marianne
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Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Los Angeles, CA 90095 USA
Harbor UCLA Med Ctr, Dept Emergency Med, Torrance, CA 90509 USA
Harbor UCLA, Los Angeles Biomed Res Inst, Torrance, CA 90509 USAChildrens Welf Teaching Hosp, Dept Pediat & Neonatal Anesthesia, Med City, Baghdad, Iraq
机构:
Sungkyunkwan Univ, Sch Med, Dept Anesthesiol, Samsung Med Ctr, Seoul, South KoreaSungkyunkwan Univ, Sch Med, Dept Anesthesiol, Samsung Med Ctr, Seoul, South Korea