Pneumocystis jirovecii infection: Cell wall (1→3)-β-D-glucan biology and diagnostic utility

被引：30

作者：

Finkelman, Malcolm A. ^{[1
]}

机构：

[1] Associates Cape Cod Inc, E Falmouth, MA 02536 USA

来源：

CRITICAL REVIEWS IN MICROBIOLOGY | 2010年 / 36卷 / 04期

关键词：

BETA-D-GLUCAN; INVASIVE FUNGAL-INFECTIONS; BRONCHOALVEOLAR LAVAGE; CYST WALL; CYTOKINE PRODUCTION; YEAST GLUCAN; CARINII; PNEUMONIA; ASSAY; COLONIZATION;

D O I：

10.3109/1040841X.2010.484001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Pneumocystis jirovecii has emerged as an important pulmonary pathogen. Historically associated with the immunocompromised, it is being increasingly observed in immunocompetent populations. (1 -> 3)-beta-D-glucan (BG) is a major component of the cyst cell wall and plays an important role in the inflammatory response to the organism. Inflammatory synergy by co-stimulation with BG and Toll-like receptor ligands has been demonstrated in vitro and may be a factor in the pathophysiology of Pneumocystis pneumonia. Detection of highly elevated serum concentrations of BG in the serum of patients has been shown to be highly sensitive for the presence of pulmonary P. jirovecii.</.

引用

页码：271 / 281

页数：11

共 50 条

[21] Serum (1→3)-β-D-glucan measurement as an early indicator of Pneumocystis jirovecii pneumonia and evaluation of its prognostic value
Held, J.
Koch, M. S.
Reischl, U.
Danner, T.
Serr, A.
CLINICAL MICROBIOLOGY AND INFECTION, 2011, 17 (04) : 595 - 602
[22] Diagnostic performance of the (1-3)-β-D-glucan assay in patients with Pneumocystis jirovecii compared with those with candidiasis, aspergillosis, mucormycosis, and tuberculosis, and healthy volunteers
Son, Hyo-Ju
Sung, Heungsup
Park, Se Yoon
Kim, Taeeun
Lee, Hyun Jeong
Kim, Sun-Mi
Chong, Yong Pil
Lee, Sang-Oh
Choi, Sang-Ho
Kim, Yang Soo
Woo, Jun Hee
Kim, Sung-Han
PLOS ONE, 2017, 12 (11):
[23] Combination of β-(1,3)-D-glucan testing in serum and qPCR in nasopharyngeal aspirate for facilitated diagnosis of Pneumocystis jirovecii pneumonia
Desoubeaux, Guillaume
Chesnay, Adelaide
Mercier, Victor
Bras-Cachinho, Jose
Moshiri, Parastou
Eymieux, Sebastien
De Kyvon, Marie-Alix
Lemaignen, Adrien
Goudeau, Alain
Bailly, Eric
MYCOSES, 2019, 62 (11) : 1015 - 1022
[24] Quantitative real-time PCR and the (1 → 3)-ß-D-glucan assay for differentiation between Pneumocystis jirovecii pneumonia and colonization
Matsumura, Y.
Ito, Y.
Iinuma, Y.
Yasuma, K.
Yamamoto, M.
Matsushima, A.
Nagao, M.
Takakura, S.
Ichiyama, S.
CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 (06) : 591 - 597
[25] Serum (1→3)-β-D-Glucan Assay for the Diagnosis of Pneumocystis jiroveci Pneumonia
del Palacio, Amalia
Soledad Cuetara, Maria
Llenas-Garcia, Jara
Elena Alvarez, Maria
Chaves, Fernando
Pulido, Federico
Catalan, Mercedes
Ponton, Jose
CLINICAL AND VACCINE IMMUNOLOGY, 2010, 17 (01) : 202 - 203
[26] Interference of (1→3)-β-D-glucan Administration in the Measurement of Plasma (1→3)-β-D-glucan
Ishizuka, Y
Tsukada, H
Gejyo, F
INTERNAL MEDICINE, 2004, 43 (02) : 97 - 101
[27] Point-Counterpoint: Should Serum β-D-Glucan Testing Be Used for the Diagnosis of Pneumocystis jirovecii Pneumonia?
Corsi-Vasquez, Gabriela
Ostrosky-Zeichner, Luis
Pilkington, Edward F., III
Sax, Paul E.
Caliendo, Angela M.
JOURNAL OF CLINICAL MICROBIOLOGY, 2020, 58 (01)
[28] Serum (1→3)-β-D-Glucan Assay for the Diagnosis of Pneumocystis jiroveci Pneumonia Reply
Del Bono, Valerio
Viscoli, Claudio
CLINICAL AND VACCINE IMMUNOLOGY, 2010, 17 (01) : 203 - 203
[29] (1→3)β-D-glucan assay positivity in patients with Pneumocystis (carinii) jiroveci pneumonia
Marty, Francisco M.
Koo, Sophia
Bryar, Julie
Baden, Lindsey R.
ANNALS OF INTERNAL MEDICINE, 2007, 147 (01) : 70 - 72
[30] The antioxidant activities of six (1 → 3)-β-D-glucan derivatives prepared from yeast cell wall
Tang, Qilin
Huang, Gangliang
Zhao, Fengying
Zhou, Lu
Huang, Shiqi
Li, Hui
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 98 : 216 - 221

← 1 2 3 4 5 →