Recent progress in the synthesis of phosphoramidate and phosphonamide derivatives: A review

被引：9

作者：

Bouchareb, Fouzia ^{[1
,2
]}

Berredjem, Malika ^{[1
]}

机构：

[1] Badji Mokhtar Annaba Univ, Dept Chem, Synth Biomol & Mol Modelling Grp, Lab Appl Organ Chem,Fac Sci, Annaba, Algeria

[2] Chadli Bendjedid EL Tarf Univ, Dept Chem, Fac Sci & Technol, El Tarf, Algeria

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2022年 / 197卷 / 07期

关键词：

Phosphoramidates; phosphonamides; synthetic methodologies; organophosphorus compounds; ONE-POT SYNTHESIS; ARYL PHOSPHATE DERIVATIVES; X-RAY CRYSTALLOGRAPHY; HEPATITIS-C VIRUS; ANTI-HIV ACTIVITY; FLAME-RETARDANT; INSECTICIDAL ACTIVITY; BIOLOGICAL EVALUATION; PROTIDE TECHNOLOGY; COTTON FABRICS;

D O I：

10.1080/10426507.2021.2012781

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

In recent years, research on organophosphorus compounds, particularly phosphoramidates PRA and phosphonamides PNA, has attracted the attention of scientists because of the manifold applications of PCR and PNA. They are formally derived from phosphoramidic acids O = P(OH)(NR2)(2), O = P(OH)(2)(NR2) and phosphonamidic acids R-PO(OH)(NR2)(2) by substitution of OH for NR2. Numerous reviews dedicated to phosphoramides and phosphonamides have been published. The purpose of this current review is to present different synthetic methodologies for the synthesis of phosphoramidates and phosphonamides by use of conventional approaches or alternative strategies under green chemistry conditions. Besides the syntheses, the corresponding reaction mechanisms and applications of these compounds are discussed.

引用

页码：711 / 731

页数：21

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