Two New Clerodane Diterpenes from Tinospora sagittata

被引：12
|
作者：
Li, Guanhua [1 ]
Ding, Wenbing [1 ,2 ]
Wan, Fanghao [1 ,3 ]
Li, Youzhi [1 ,2 ]
机构：
[1] Hunan Agr Univ, Coll Plant Protect, Changsha 410128, Hunan, Peoples R China
[2] Hunan Coinnovat Ctr Utilizat Bot Funct Ingredient, Changsha 410128, Hunan, Peoples R China
[3] Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China
来源：
MOLECULES | 2016年 / 21卷 / 09期
关键词：
Tinospora sagittata; clerodane diterpenes; alpha-glucosidase inhibitory activity; PLANTS; ROOTS;
D O I：
10.3390/molecules21091250
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new clerodane-type diterpenes, tinosporins C (1) and tinosporins D (2) were isolated from the stems of Tinospora sagittata (Oliv.), together with three known ones, columbin (3), tinophylloloside (4), and tinospinoside D (5). The structures of these compounds were determined on the basis of spectroscopic data interpretation, with that of the absolute configuration of compound 1 was assigned by experimental and calculated ECD spectra. The cytotoxicity and -glucosidase inhibitory activities of isolated compounds were evaluated in vitro.
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页数：8
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