Economic drivers and trade-offs in antibody purification processes

被引：0
|
作者：
Farid, Suzanne S. [1 ]
机构：
[1] UCL, Adv Ctr Biochem Engn, Dept Biochem Engn, London, England
来源：
BIOPHARM INTERNATIONAL | 2008年
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Increasing titers in mammalian cell culture has recently shifted the focus of process development efforts towards improving the economics of product recovery and purification processes. Some argue that a paradigm shift may be required to ensure timely and cost-effective delivery of future antibody candidates. This paper discusses the key process economic drivers and the impact of scale and titer on downstream processing (DSP) economic trade-offs.
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收藏
页码：37 / 42
页数：6
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