Ion-mediated conformational switches

被引：86
|
作者：
Knipe, Peter C. [1 ]
Thompson, Sam [1 ]
Hamilton, Andrew D. [1 ]
机构：
[1] Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England
来源：
CHEMICAL SCIENCE | 2015年 / 6卷 / 03期
关键词：
MECHANOSENSITIVE CHANNEL; MOLECULAR RECOGNITION; ANION RECOGNITION; HELICITY CONTROL; MOTION; SELECTIVITY; RECEPTORS; CAVITANDS; INVERSION; FOLDAMERS;
D O I：
10.1039/c4sc03525a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Molecular switches are ubiquitous in Nature and provide the basis of many forms of transport and signalling. Single synthetic molecules that change conformation, and thus function, reversibly in a stimulus-dependent manner are of great interest not only to chemists but society in general; myriad applications exist in storage, display, sensing and medicine. Here we describe recent developments in the area of ion-mediated switching.
引用
收藏
页码：1630 / 1639
页数：10
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