Structural Diversity and Biological Potential of Alkaloids from the Genus Hippeastrum, Amaryllidaceae: an Update

被引:1
|
作者
Tallini, Luciana R. [1 ,2 ]
Giordani, Raquel B. [3 ]
de Andrade, Jean Paulo [4 ]
Bastida, Jaume [2 ]
Zuanazzi, Jose Angelo S. [1 ]
机构
[1] Univ Fed Rio Grande do Sul, Fac Farm, Programa Posgrad Ciencias Farmaceut, BR-90610000 Porto Alegre, RS, Brazil
[2] Univ Barcelona, Fac Farm & Ciencies Alimentacio, Dept Biol Sanitat & Medi Ambient, Grp Productes Nat, Barcelona 08028, Spain
[3] Univ Fed Rio Grande do Norte, Dept Farm, BR-59012570 Natal, RN, Brazil
[4] Univ Talca, Inst Invest Interdisciplinaria, Vicerrectoria Acad, Campus Talca, Talca 3460000, Chile
关键词
Alzheimer's disease; Anti-inflammatory; Antitumoral; Antiparasitic; Cytotoxic; Isoquinoline alkaloids; ABSOLUTE-CONFIGURATION; INHIBITORY-ACTIVITIES; CYTOTOXIC ACTIVITIES; NARCICLASINE; CANCER; BIOSYNTHESIS; GALANTAMINE; LYCORINE; DRUG; HAEMANTHAMINE;
D O I
10.1007/s43450-021-00211-z
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The subfamily Amaryllidoideae, Amaryllidaceae, presents an exclusive group of structures known as Amaryllidaceae alkaloids, which have a broad spectrum of biological activities. These plants are classified into 59 genera, including Hippeastrum Herb., which comprises approximately 60 species distributed mainly in South America, being widely used as ornamental plants due to the beauty of its flowers. This review presents an update about the alkaloid profiling of Hippeastrum extracts published between 2012 and 2021, as well as an approach to the biological potential of these compounds.
引用
收藏
页码:648 / 657
页数:10
相关论文
共 50 条
  • [31] Chemical composition and anticholinesterase activity of cultivated bulbs from Hippeastrum elegans, a potential tropical source of bioactive alkaloids
    de Paiva, Jose Regis
    de Queiroz Souza, Ana Sheila
    de Cassia Alves Pereira, Rita
    Ribeiro, Paulo Riceli Vasconcelos
    Filho, Elenilson Godoy Alves
    Silva, Lorena Mara Alexandre e
    Zocolo, Guilherme Juliao
    de Brito, Edy Sousa
    Alves, Daniela Ribeiro
    de Morais, Selene Maia
    Tavares, Juliete
    das Chagas Lima Pinto, Francisco
    de Andrade, Geanne Matos
    Pessoa, Otilia Deusdenia Loiola
    Canuto, Kirley Marques
    PHYTOCHEMISTRY LETTERS, 2021, 43 : 27 - 34
  • [32] Amaryllidaceae Alkaloids as Potential Inhibitors of the Trypanosoma cruzi Transsialidase Enzyme: Unique Insights from Computational Studies
    Borquaye, Lawrence Sheringham
    Manu, Prince
    Mensah, Jehoshaphatt
    Gasu, Edward
    Laryea, Michael
    Darko, Godfred
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (03) : S267 - S267
  • [33] Overview of the Ruspolia Plant Genus: Insights into Its Chemical Diversity and Biological Potential
    Bailly, Christian
    Vergoten, Gerard
    LIFE-BASEL, 2025, 15 (02):
  • [34] Chemical and Biological Aspects of Different Species of the Genus Clinanthus Herb. (Amaryllidaceae) from South America
    Rodriguez-Escobar, Maria Lenny
    Tallini, Luciana R.
    Lisa-Molina, Julia
    Berkov, Strahil
    Viladomat, Francesc
    Meerow, Alan
    Bastida, Jaume
    Torras-Claveria, Laura
    MOLECULES, 2023, 28 (14):
  • [35] Structural Diversity and Biological Activities of the Cyclodipeptides from Fungi
    Wang, Xiaohan
    Li, Yuying
    Zhang, Xuping
    Lai, Daowan
    Zhou, Ligang
    MOLECULES, 2017, 22 (12):
  • [36] A Comprehensive Appraisal of Bisbenzylisoquinoline Alkaloids Isolated From Genus Cyclea for Anticancer Potential
    Valsan, Alisha
    Omanakuttan, Vishnu K.
    Radhakrishnan, Kokuvayil Vasu
    Maiti, Kaustabh Kumar
    JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2025, 39 (02)
  • [37] Amaryllidaceae Alkaloids of Different Structural Types from Narcissus L. cv. Professor Einstein and Their Cytotoxic Activity
    Breiterova, Katerina
    Koutova, Darja
    Marikova, Jana
    Havelek, Radim
    Kunes, Jiri
    Majorosova, Martina
    Opletal, Lubomir
    Host'alkova, Anna
    Jenco, Jaroslav
    Rezacova, Martina
    Cahlikova, Lucie
    PLANTS-BASEL, 2020, 9 (02):
  • [38] Chemical Composition and Biological Potential of Plants from the Genus Bauhinia
    Cechinel Filho, Valdir
    PHYTOTHERAPY RESEARCH, 2009, 23 (10) : 1347 - 1354
  • [39] Structural diversity, biosynthesis, and biological functions of lipopeptides from Streptomyces
    Zhang, Songya
    Chen, Yunliang
    Zhu, Jing
    Lu, Qiujie
    Cryle, Max J.
    Zhang, Youming
    Yan, Fu
    NATURAL PRODUCT REPORTS, 2023, 40 (03) : 557 - 594
  • [40] Natural Products from the Poles: Structural Diversity and Biological Activities
    Gustavo Souza dos Santos
    Thaiz Rodrigues Teixeira
    Pio Colepicolo
    Hosana Maria Debonsi
    Revista Brasileira de Farmacognosia, 2021, 31 : 531 - 560