Simple method for the synthesis of 1-substituted β-carboline derivatives from tryptamine and carboxylic acids in polyphosphoric acid

被引：19

作者：

Ivanov, I ^{[1
]}

Nikolova, S ^{[1
]}

Statkova-Abeghe, S ^{[1
]}

机构：

[1] Paisij Hilendarski Univ Plovdiv, Dept Organ Chem, BG-4000 Plovdiv, Bulgaria

来源：

HETEROCYCLES | 2005年 / 65卷 / 10期

关键词：

D O I：

10.3987/COM-05-10484

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A number of 1-substituted 3,4-dihydro-9H-beta-carboline derivatives (4) with high purity and yields have been synthesized by treating of tryptamine (1) with carboxylic acids (2) in polyphosphoric acid. 3,4-Dihydro-9H-beta-carbolines (4) were successfully transformed to 1,2,3,4-tetrahydro-9H-beta-carbolines (5) and 9H-beta-carbolines (6).

引用

页码：2483 / 2492

页数：10

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