Study of the application of multiway multivariate techniques to model data from an industrial fermentation process

被引:27
|
作者
Ferreira, Ana P. [1 ]
Lopes, Joao A. [1 ]
Menezes, Jose C. [1 ]
机构
[1] Univ Tecn Lisboa, Inst Super Tecn, Ctr Biol & Chem Engn, P-1049001 Lisbon, Portugal
关键词
industrial fermentation; multivariate analysis; batch process; multiway principal component analysis; multiway partial least squares; MONITORING BATCH PROCESSES; PRINCIPAL COMPONENT ANALYSIS; PARTIAL LEAST-SQUARES; STATISTICAL-ANALYSIS; CLAVULANIC ACID; SUPERVISION; MULTIBLOCK; DIAGNOSIS; PLS;
D O I
10.1016/j.aca.2007.05.007
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Several multivariate statistical techniques have been extensively proposed for monitoring industrial processes. In this paper, multiway extensions of two such techniques: multiway principal component analysis (MPCA) and multiway partial least squares regression (MPLS) were applied to a large data set from an industrial pilot-scale fermentation process to improve process knowledge. The MPCA model is able to diagnose faults occurring in the process whether they affect or not process productivity while the MPLS model enables the prediction of final product concentration and the detection of faults that will influence the fermentation productivity. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:120 / 127
页数:8
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