A Placebo-Controlled Trial of Atomoxetine in Marijuana-Dependent Individuals with Attention Deficit Hyperactivity Disorder

被引：59
|
作者：
McRae-Clark, Aimee L. [1 ]
Carter, Rickey E. [2 ]
Killeen, Therese K. [1 ]
Carpenter, Matthew J. [1 ]
White, Kathleen G. [1 ]
Brady, Kathleen T. [1 ]
机构：
[1] Med Univ S Carolina, Dept Psychiat & Behav Sci, Charleston, SC 29425 USA
[2] Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
来源：
AMERICAN JOURNAL ON ADDICTIONS | 2010年 / 19卷 / 06期
关键词：
DEFICIT/HYPERACTIVITY DISORDER; SUBSTANCE-ABUSE; ADULT ADHD; SUBTHRESHOLD DIAGNOSES; LATE-ONSET; FOLLOW-UP; ALCOHOL; METHYLPHENIDATE; COMORBIDITY; COGNITION;
D O I：
10.1111/j.1521-0391.2010.00076.x
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
This study evaluated the effects of atomoxetine on the symptoms of attention deficit hyperactivity disorder (ADHD) and marijuana use in marijuana-dependent adults. In conjunction with motivational interviewing, participants received either atomoxetine (n = 19) or matching placebo (n = 19) for 12 weeks. Participants randomized to atomoxetine had greater improvement in ADHD on the Clinical Global Impression-Improvement scale than participants treated with placebo. No treatment group differences in self-rated ADHD symptoms, overall Wender-Reimherr Adult Attention Deficit Disorder Scale scores, or marijuana use outcomes were noted. These results suggest that atomoxetine may improve some ADHD symptoms but does not reduce marijuana use in this population. (Am J Addict 2010;00:1-9).
引用
收藏
页码：481 / 489
页数：9
相关论文
共 50 条
  • [31] A double-blind, placebo-controlled withdrawal trial of dexmethylphenidate hydrochloride in children with attention deficit hyperactivity disorder
    Arnold, LE
    Lindsay, RL
    Conners, CK
    Wigal, SB
    Levine, AJ
    Johnson, DE
    West, SA
    Sangal, RB
    Bohan, TP
    Zeldis, JB
    JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2004, 14 (04) : 542 - 554
  • [32] Atomoxetine for the treatment of attention-deficit/hyperactivity disorder
    Davids, E
    Gastpar, M
    FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE, 2004, 72 (10) : 586 - 591
  • [33] Atomoxetine for Attention Deficit Hyperactivity Disorder in Mental Retardation
    Fernandez-Jaen, Alberto
    Martin Fernandez-Mayoralas, Daniel
    Calleja Perez, Beatriz
    Munoz Jareno, Nuria
    Campos Diaz, Maria del Rosario
    PEDIATRIC NEUROLOGY, 2010, 43 (05) : 341 - 347
  • [34] Atomoxetine treatment of attention-deficit/hyperactivity disorder
    Eiland, LS
    Guest, AL
    ANNALS OF PHARMACOTHERAPY, 2004, 38 (01) : 86 - 90
  • [35] Once-Daily Treatment With Atomoxetine in Adults With Attention-Deficit/Hyperactivity Disorder: A 24-Week, Randomized, Double-Blind, Placebo-Controlled Trial
    Young, Joel L.
    Sarkis, Elias
    Qiao, Meihua
    Wietecha, Linda
    CLINICAL NEUROPHARMACOLOGY, 2011, 34 (02) : 51 - 60
  • [36] A randomized, double-blind, placebo-controlled clinical trial on once-daily atomoxetine hydrochloride in taiwanese children and adolescents with attention-deficit/hyperactivity disorder
    Gau, Susan S. F.
    Huang, Yu-Shu
    Soong, Wei-Tsuen
    Chou, Miao-Chun
    Chou, Wen-Jiun
    Shang, Chi-Yung
    Tseng, Wan-Ling
    Allen, Albert J.
    Lee, Phil
    JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2007, 17 (04) : 447 - 460
  • [37] A randomized, placebo-controlled clinical trial of bupropion for the prevention of smoking in children and adolescents with attention-deficit/hyperactivity disorder
    Monuteaux, Michael C.
    Spencer, Thomas J.
    Faraone, Stephen V.
    Wilson, Angela M.
    Biederman, Joseph
    JOURNAL OF CLINICAL PSYCHIATRY, 2007, 68 (07) : 1094 - 1101
  • [38] Micronutrients for Attention-Deficit/Hyperactivity Disorder in Youths: A Placebo-Controlled Randomized Clinical Trial,"A Placebo-Controlled Randomized Clinical Trial (vol 61, pg 647, 2022)
    Johnstone
    JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2023, 62 (05): : 607 - 607
  • [39] Ginkgo biloba in the treatment of attention-deficit/hyperactivity disorder in children and adolescents. A randomized, placebo-controlled, trial
    Shakibaei, Fereshteh
    Radmanesh, Mehrsa
    Salari, Elham
    Mahaki, Behzad
    COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE, 2015, 21 (02) : 61 - 67
  • [40] Bupropion XL in adults with attention-deficit/hyperactivity disorder: A randomized, placebo-controlled study
    Wilens, TE
    Haight, BR
    Horrigan, JP
    Hudziak, JJ
    Rosenthal, NE
    Connor, DF
    Hampton, KD
    Richard, NE
    Modell, JG
    BIOLOGICAL PSYCHIATRY, 2005, 57 (07) : 793 - 801
12345