Retinal Nerve Fiber Layer Thickness in Prediabetic Patients

被引:4
|
作者
Bilen, Arzu [1 ]
Ates, Orhan [2 ]
Ondas, Osman [2 ]
Bilen, Habib [3 ]
Capoglu, Ilyas [3 ]
机构
[1] Univ Ataturk, Sch Med, Dept Internal Med, Erzurum, Turkey
[2] Univ Ataturk, Dept Ophtalmol, Sch Med, Erzurum, Turkey
[3] Univ Ataturk, Dept Internal Med, Div Endocrinol & Metab, Sch Med, Erzurum, Turkey
来源
EURASIAN JOURNAL OF MEDICINE | 2022年 / 54卷 / 01期
关键词
Prediabetes; diabetic retinopathy; retinal nerve fiber layer thickness; spectral-domain optical coherence tomography; IMPAIRED GLUCOSE-TOLERANCE; DIABETIC-RETINOPATHY; RISK-FACTORS; PREVALENCE;
D O I
10.5152/eurasianjmed.2022.20420
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Diabetic retinopathy is a leading cause of blindness. Diabetic retinopathy is not only seen in diabetic patients with the clinical diagnosis but also in prediabetic patients. The aim of this study is to evaluate the RNFL thickness in prediabetic patients. Materials and Methods: In this study, 50 prediabetic patients and 50 healthy individuals were included. RNFL measurements were performed with SD-OCT in patients with prediabetes and healthy controls. Results: The mean RNFL thickness for the prediabetic group was 94.7 +/- 6.3 mu m, inferior quadrant (120 +/- 11.6), superior quadrant (112.3 +/- 14.13), nasal quadrant (71 +/- 12.9), and temporal quadrant (653 +/- 9.2 mu m). The mean RNFL thickness for the control group was 98.9 +/- 7.5 mu m, inferior quadrant (128 +/- 14.7), superior quadrant (116.3 +/- 15.12), nasal quadrant (77 +/- 15.8), and temporal quadrant (71.2 +/- 10.3 mu m). Variance analysis demonstrated that the RNFL thickness difference between the groups was significant in all quadrants (P < .001). Conclusion: RNLF thinning can be seen in prediabetic patients before obvious vascular damage has occurred, and it may present in prediabetic patients not only in the temporal quadrant but also in all quadrants. The early retinal neural changes shown in this study in prediabetic patients may help to better understand the process leading to diabetic overt retinopathy.
引用
收藏
页码:8 / 11
页数:4
相关论文
共 50 条
  • [21] Retinal Nerve Fiber Layer Thickness in Various Retinal Diseases
    Lim, Hyung-Bin
    Sung, Jae-Yun
    Ahn, Seung-Il
    Jo, Young-Joon
    Kim, Jung-Yeul
    OPTOMETRY AND VISION SCIENCE, 2018, 95 (03) : 247 - 255
  • [22] Retinal nerve fiber layer, retinal pigment epithelium, and choroidal thickness in vitiligo patients
    Oncul, Hasan
    Ayhan, Erhan
    JOURNAL OF COSMETIC DERMATOLOGY, 2020, 19 (11) : 3032 - 3037
  • [23] Peripapillary retinal nerve fiber layer thickness in patients with unilateral retinal vein occlusion
    Jayoung Ahn
    Daniel Duck-Jin Hwang
    Scientific Reports, 11
  • [24] Is Retinal Oxygen Saturation Related to Retinal Nerve Fiber Layer Thickness in Glaucoma Patients?
    Hammer, Martin
    Ramm, Lisa
    Peters, Sven
    Sauer, Lydia
    Augsten, Regine
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2014, 55 (13)
  • [25] Peripapillary retinal nerve fiber layer thickness in patients with unilateral retinal vein occlusion
    Ahn, Jayoung
    Hwang, Daniel Duck-Jin
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [26] Retinal Nerve Fiber Layer Progression in Glaucoma A Comparison between Retinal Nerve Fiber Layer Thickness and Retardance
    Xu, Guihua
    Weinreb, Robert N.
    Leung, Christopher K. S.
    OPHTHALMOLOGY, 2013, 120 (12) : 2493 - 2500
  • [27] Retinal nerve fiber layer thickness in the pediatric population
    Lee, PS
    Hall, L
    Piette, S
    Ishikawa, H
    Heiser, L
    Shippman, S
    Liebmann, JM
    Ritch, R
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2002, 43 : U602 - U602
  • [28] Evaluation of retinal nerve fiber layer thickness in migraine
    Sorkhabi, Rana
    Mostafaei, Somaiyeh
    Ahoor, Mohammadhosein
    Talebi, Mahnaz
    IRANIAN JOURNAL OF NEUROLOGY, 2013, 12 (02) : 51 - 55
  • [29] Retinal nerve fiber layer thickness in amblyopic eyes
    Lempert, Philip
    AMERICAN JOURNAL OF OPHTHALMOLOGY, 2007, 143 (01) : 190 - 191
  • [30] Retinal Nerve Fiber Layer Thickness in Opioid Abusers
    Karadere, M. Mehmet
    Sahin, Tayfun
    Cobanoglu, Ebru
    Yildiz, Veysi
    PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, 2020, 30 (04) : 369 - 373