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HIV-1 genotypic resistance: automated sequence analysis and interpretation
被引:1
|作者:
Goujon, CP
Schneider, VM
Jacomet, C
Nicolas, JC
机构:
[1] Hop Rothschild, Inst Federatif St Antoine Rech Sante, Microbiol Serv, F-75571 Paris, France
[2] Hop Rothschild, Serv Malad Infect & Trop, F-75571 Paris, France
关键词:
D O I:
10.1093/bioinformatics/14.10.886
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
We present here GRANT (Genotypic Resistance Analysis Tool), a program that automatically detects resistance-related mutations in HIV-1 protein sequences, and comments on the degree of resistance conferred when possible. This program is easily user-customizable, allowing immediate updates as new resistance mutations are discovered, or use with an organism other than HIV.
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页码:886 / 887
页数:2
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