Extensive Methylation of SFFV Promoter Sequences Does Not Allow Lentiviral Transgene Expression In Vivo

被引：0
|
作者：
Herbst, Friederike [1 ,2 ]
Ball, Claudia R. [1 ,2 ]
Tuorto, Francesca [2 ]
Wang, Wei [2 ]
Kloz, Ulrich [2 ]
van der Hoeven, Franciscus [2 ]
Lyko, Frank [2 ]
Schmidt, Manfred [1 ,2 ]
von Kalle, Christof [1 ,2 ]
Glimm, Hanno [1 ,2 ]
机构：
[1] Natl Ctr Tumour Dis NCT, Heidelberg, Germany
[2] German Canc Res Ctr, Heidelberg, Germany
来源：
HUMAN GENE THERAPY | 2010年 / 21卷 / 09期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：1203 / 1203
页数：1
相关论文
共 50 条
  • [11] Transgene Expression Is Associated with Copy Number and Cytomegalovirus Promoter Methylation in Transgenic Pigs
    Kong, Qingran
    Wu, Meiling
    Huan, Yanjun
    Zhang, Li
    Liu, Haiyan
    Bou, Gerelchimeg
    Luo, Yibo
    Mu, Yanshuang
    Liu, Zhonghua
    PLOS ONE, 2009, 4 (08):
  • [12] Does COMT promoter methylation regulate gene expression?
    Dempster, EL
    Mill, J
    Craig, IW
    Collier, DA
    AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 2005, 138B (01) : 83 - 83
  • [13] Ex vivo and in vitro studies of transgene expression in rat astrocytes transduced with lentiviral vectors
    Ericson, C
    Wictorin, K
    Lundberg, C
    EXPERIMENTAL NEUROLOGY, 2002, 173 (01) : 22 - 30
  • [14] A lentiviral vector with novel multiple cloning sites: Stable transgene expression in vitro and in vivo
    Santhosh, C. V.
    Tamhane, Mayur C.
    Kamat, Rohan H.
    Patel, Vainav V.
    Mukhopadhyaya, Robin
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 371 (03) : 546 - 550
  • [15] TAGGING GENOMIC SEQUENCES THAT DIRECT TRANSGENE EXPRESSION BY ACTIVATION OF A PROMOTER TRAP IN PLANTS
    LINDSEY, K
    WEI, WB
    CLARKE, MC
    MCARDLE, HF
    ROOKE, LM
    TOPPING, JF
    TRANSGENIC RESEARCH, 1993, 2 (01) : 33 - 47
  • [16] Physiological regulation of transgene expression by a lentiviral vector containing the A2UCOE linked to a myeloid promoter
    Brendel, C.
    Mueller-Kuller, U.
    Schultze-Strasser, S.
    Stein, S.
    Chen-Wichmann, L.
    Krattenmacher, A.
    Kunkel, H.
    Dillmann, A.
    Antoniou, M. N.
    Grez, M.
    GENE THERAPY, 2012, 19 (10) : 1018 - 1029
  • [17] Physiological Regulation of Transgene Expression by a Lentiviral Vector Containing the A2UCOE Linked to a Myeloid Promoter
    Brendel, Christian
    Mueller-Kuller, Uta
    Schultze-Strasser, Stephan A.
    Stein, Stefan
    Chen-Wichmann, Linping
    Kunkel, Hana
    Antoniou, Miachael N.
    Grez, Manuel
    MOLECULAR THERAPY, 2012, 20 : S195 - S196
  • [18] Physiological regulation of transgene expression by a lentiviral vector containing the A2UCOE linked to a myeloid promoter
    C Brendel
    U Müller-Kuller
    S Schultze-Strasser
    S Stein
    L Chen-Wichmann
    A Krattenmacher
    H Kunkel
    A Dillmann
    M N Antoniou
    M Grez
    Gene Therapy, 2012, 19 : 1018 - 1029
  • [19] Promoter analysis of the neuronal nicotinic acetylcholine receptor α4 gene:: methylation and expression of the transgene
    Watanabe, H
    Zoli, M
    Changeux, JP
    EUROPEAN JOURNAL OF NEUROSCIENCE, 1998, 10 (07) : 2244 - 2253
  • [20] Effect of lentiviral promoter and fetal route of administration on transgene biodistribution and expression in rhesus monkeys (Macaca mulatta)
    Jimenez, DF
    Lee, CI
    O'Shea, CE
    Kohn, DB
    Tarantal, AF
    MOLECULAR THERAPY, 2004, 9 : S378 - S378
12345