Catheter electrode studies for ultra-short high-field pulses

被引：0

作者：

Thu, M ^{[1
]}

Behrend, MR ^{[1
]}

Vernier, PT ^{[1
]}

Sun, YH ^{[1
]}

Kuthi, A ^{[1
]}

Marcu, L ^{[1
]}

Gundersen, MA ^{[1
]}

机构：

[1] Univ So Calif, Dept Biomed Engn, Los Angeles, CA 90089 USA

来源：

PROCEEDINGS OF THE 26TH INTERNATIONAL POWER MODULATOR SYMPOSIUM AND 2004 HIGH VOLTAGE WORKSHOP, CONFERENCE RECORD | 2004年

关键词：

D O I：

暂无

中图分类号：

TE [石油、天然气工业]; TK [能源与动力工程];

学科分类号：

0807 ; 0820 ;

摘要：

Ultra-short (less than 30 ns) high-field (greater than 1.5 megavolt per meter (MV/m)) pulses have been shown to induce apoptosis in cultured cancer-derived cells. A potential clinical application of this phenomenon is to treat malignant and diseased tissues. This paper presents preliminary research on development and design of thin, flexible catheter electrodes to deliver nanosecond pulses for minimally invasive in vivo treatment applications. An evaluation of commercially available microwave cables and RF ablation catheters for compatibility with ultra-short pulse cancer therapy is presented. The results show that RF ablation catheters distort high frequency components of nanosecond pulses. Preliminary results of a prototype micro-coaxial catheter electrode for nanosecond pulse delivery applications are presented.

引用

页码：337 / 340

页数：4

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