Synthesis and configuration of (1S,3R)- and (1R,3R)-1-(3,4-dimethoxyphenyl)-1,3-dimethyl-1,3-dihydroisobenzofurans

被引：3
|
作者：
Shishkina, Irina N. [1 ]
Demyanovich, Valeriya M. [1 ]
Potekhin, Konstantin A. [2 ]
Gurbanov, Atash V. [3 ]
Zefirov, Nikolay S. [1 ]
机构：
[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
[2] AG & NG Stoletov Vladimir State Univ, Vladimir 600000, Russia
[3] Baku State Univ, Dept Organ Chem, AZ-1148 Baku, Azerbaijan
来源：
MENDELEEV COMMUNICATIONS | 2015年 / 25卷 / 01期
关键词：
SEROTONIN TRANSPORTER; CITALOPRAM; 1,3-DIHYDROISOBENZOFURANS; PHTHALANS; ALCOHOLS; ROUTE;
D O I：
10.1016/j.mencom.2015.01.002
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Cyclization of iodides of diastereomeric 1-(1-aryl-1-hydroxyethyl)-2-(1-trimethylammonioethyl)benzenes, derived from (S)-1-phenylethanamine, proceeds diastereospecifically to afford (1S,3R)- and (1R,3R)-1-aryl-1,3-dimethyl-1,3-dihydroisobenzofurans, the potent antidepressants.
引用
收藏
页码：11 / 12
页数：2
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