Characterization, antifungal and cytotoxic evaluation of green synthesized zinc oxide nanoparticles using Ziziphus nummularia leaf extract

被引：107
|
作者：
Padalia, Hemali [1 ]
Chanda, Sumitra [1 ]
机构：
[1] Saurashtra Univ, Dept Biosci UGC CAS, Rajkot, Gujarat, India
来源：
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY | 2017年 / 45卷 / 08期
关键词：
Zinc oxide nanoparticles; green synthesis; Ziziphus nummularia; antifungal activity; cytotoxic activity; SILVER NANOPARTICLES; ZNO NANOPARTICLES; PSEUDOMONAS-AERUGINOSA; ANTIBACTERIAL ACTIVITY; CANDIDA-ALBICANS; SIZE; CELL; NANOCRYSTALS; GENOTOXICITY; RESISTANCE;
D O I：
10.1080/21691401.2017.1282868
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Zinc oxide nanoparticles (ZnO NPs) were synthesized using Ziziphus nummularia leaf extract. The characterization was done by various spectral analysis and antifungal (anti-candidal) activity against multidrug resistant clinical isolates and their cytotoxic potential was evaluated. The ZnO NPs were 17.33nm in size and were spherical/irregular in shape. The antifungal activity of ZnO NPs was better than four standard azole antibiotics and they also showed potent cytotoxic effect against HeLa cancer cell line. The results strongly suggest the applicability of green synthesized ZnO NPs as antifungal agent and also its use in cancer diagnosis and treatment.
引用
收藏
页码：1751 / 1761
页数：11
相关论文
共 50 条
  • [31] Unveiling the Antibacterial, Antifungal, and Cytotoxic Potential of Selenium Nanoparticles Synthesized with Syzygium cumini Leaf Extract
    Devi, Haorongbam Joldy
    Gnanasekaran, Prathiba
    Kumar, Arumugam Madan
    Siva, Durairaj
    Devi, Yumnam Asha
    JOURNAL OF CLUSTER SCIENCE, 2025, 36 (02)
  • [32] Green biosynthesis of zinc and selenium oxide nanoparticles using callus extract of Ziziphus spina-christi: characterization, antimicrobial, and antioxidant activity
    Islam lashin
    Mohamed Hasanin
    Sayed A. M. Hassan
    Amr Hosny Hashem
    Biomass Conversion and Biorefinery, 2023, 13 : 10133 - 10146
  • [33] Green biosynthesis of zinc and selenium oxide nanoparticles using callus extract of Ziziphus spina-christi: characterization, antimicrobial, and antioxidant activity
    Lashin, Islam
    Hasanin, Mohamed
    Hassan, Sayed A. M.
    Hashem, Amr Hosny
    BIOMASS CONVERSION AND BIOREFINERY, 2023, 13 (11) : 10133 - 10146
  • [34] Evaluation of photocatalytic activity, antibacterial and cytotoxic effects of green synthesized ZnO nanoparticles by Sechium edule leaf extract
    N. Elavarasan
    K. Kokila
    G. Inbasekar
    V. Sujatha
    Research on Chemical Intermediates, 2017, 43 : 3361 - 3376
  • [35] Antibacterial Evaluation of Cuprous Oxide Nanoparticles Synthesized Using Leaf Extract of Callistemon viminalis
    Sharma, Deepika
    Thakur, Nutan
    Vashistt, Jitendraa
    Bisht, Gopal Singh
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2018, 52 (03) : 449 - 455
  • [36] Evaluation of photocatalytic activity, antibacterial and cytotoxic effects of green synthesized ZnO nanoparticles by Sechium edule leaf extract
    Elavarasan, N.
    Kokila, K.
    Inbasekar, G.
    Sujatha, V.
    RESEARCH ON CHEMICAL INTERMEDIATES, 2017, 43 (05) : 3361 - 3376
  • [37] Characterization and biological activities of synthesized zinc oxide nanoparticles using the extract of Acantholimon serotinum
    Karimzadeh, Mohammad Reza
    Soltanian, Sara
    Sheikhbahaei, Mahboubeh
    Mohamadi, Neda
    GREEN PROCESSING AND SYNTHESIS, 2020, 9 (01) : 722 - 733
  • [38] Green Synthesis of Zinc Oxide Nanoparticles Using Aqueous Extract of Deverra tortuosa and their Cytotoxic Activities
    Yasser A. Selim
    Maha A. Azb
    Islam Ragab
    Mohamed H. M. Abd El-Azim
    Scientific Reports, 10
  • [39] Green Synthesis of Zinc Oxide Nanoparticles Using Aqueous Extract of Deverra tortuosa and their Cytotoxic Activities
    Selim, Yasser A.
    Azb, Maha A.
    Ragab, Islam
    Abd El-Azim, Mohamed H. M.
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [40] Cytotoxic Potential of Biogenic Zinc Oxide Nanoparticles Synthesized From Swertia chirayita Leaf Extract on Colorectal Cancer Cells
    Berehu, Hadgu Mendefro
    Khan, Md Imran
    Chakraborty, Rajasree
    Lavudi, Kousalya
    Penchalaneni, Josthna
    Mohapatra, Bibhashee
    Mishra, Amrita
    Patnaik, Srinivas
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021, 9
12345