Palladium-catalyzed intramolecular δ-lactam formation of aryl halides and amide-enolates:: Syntheses of cherylline and latifine

被引:76
|
作者
Honda, T [1 ]
Namiki, H [1 ]
Satoh, F [1 ]
机构
[1] Hoshi Univ, Fac Pharmaceut Sci, Shinagawa Ku, Tokyo 1428501, Japan
关键词
D O I
10.1021/ol0155337
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Palladium-catalyzed intramolecular carbon-carbon bond formation of aryl halides and amide enolates gave 4-arylisoquinoline derivatives in good yields, which were further converted into the isoquinoline alkaloids cherylline and latifine.
引用
收藏
页码:631 / 633
页数:3
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