CGRP-immunoreactive nerve fibers projecting to lumbar facet joints through the paravertebral sympathetic trunk in rats

被引：37

作者：

Suseki, K ^{[1
]}

Takahashi, Y ^{[1
]}

Takahashi, K ^{[1
]}

Chiba, T ^{[1
]}

Tanaka, K ^{[1
]}

Moriya, H ^{[1
]}

机构：

[1] CHIBA UNIV,SCH MED,DEPT ANAT,CHUO KU,CHIBA 260,JAPAN

来源：

NEUROSCIENCE LETTERS | 1996年 / 221卷 / 01期

关键词：

low back pain; sensory innervation; visceral sensory; sympathetic nervous system; interaction; fluorescent carbocyanine dye (DiI); retrograde tracing method; immunohistochemistry;

D O I：

10.1016/S0304-3940(96)13282-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We previously reported that the L5-6 facet joint is innervated from DRGs from L1 to L5 and the paravertebral sympathetic ganglia from T12 to L6 in rats. In the present study, to determine the sensory pathway from the L5-6 facet joint, we placed the fluorescent carbocyanine dye, DiI, in the L5-6 facet joint, and examined the paravertebral sympathetic trunks and ganglia bilaterally. We found some DiI-labeled nerve fibers exhibiting calcitonin gene-related peptide (CGRP)-immunoreactivity, and some DiI-labeled neurons surrounded by CGRP-immunoreactive varicose fibers in the ganglia. The results suggest that a sensory pathway from the L5-6 facet joint to L1 and/or L2 DRGs is present in the paravertebral sympathetic trunk, and that sensory nerve fibers may connect with sympathetic postganglionic neurons projecting to lumbar facet joints. (C) 1996 Elsevier Science Ireland Ltd.

引用

页码：41 / 44

页数：4

共 28 条

[21] Lumbar posterolateral fusion inhibits sensory nerve ingrowth into punctured lumbar intervertebral discs and upregulation of CGRP immunoreactive DRG neuron innervating punctured discs in rats
Koshi, Takana
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EUROPEAN SPINE JOURNAL, 2010, 19 (04) : 593 - 600
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Ohtori, S
Takahashi, K
Chiba, T
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Sameda, H
Moriya, H
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 2001, 94 (1-2): : 132 - 135
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ARCHIVES OF HISTOLOGY AND CYTOLOGY, 1988, 51 (01) : 91 - 98
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JOURNAL OF MOLECULAR NEUROSCIENCE, 1991, 3 (01) : 7 - 18
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Ohtori, S
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SPINE, 2001, 26 (09) : 1009 - 1013
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NEUROSCIENCE LETTERS, 1991, 133 (02) : 249 - 252
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NEUROSCIENCE LETTERS, 2002, 323 (02) : 129 - 132
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NEUROSCIENCE LETTERS, 1985, 57 (02) : 169 - 174

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