General Two-Step Preparation of Chalcones Containing Thiazole

被引：9

作者：

Tazoo, Dagobert ^{[1
,2
]}

Oniga, Ovidiu ^{[3
]}

Bohle, D. Scott ^{[2
]}

Chua, Zhijie ^{[2
]}

Dongo, Etienne ^{[1
]}

机构：

[1] Univ Yaounde I, Dept Organ Chem, Yaounde, Cameroon

[2] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada

[3] Univ Med & Pharm Iuliu Hatieganu, Dept Pharmaceut Chem, Cluj Napoca 400010, Romania

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 49卷 / 04期

基金：

加拿大自然科学与工程研究理事会;

关键词：

CONSTITUENTS; DERIVATIVES; INHIBITORS;

D O I：

10.1002/jhet.853

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Aryl-4-methyl-5-acetylthiazoles, which were prepared from arylthioamides and chloroacetylacetone, were treated with 6-substituted-3-formylchromones or arylaldehydes to give a series of eighteen new thiazolylchalcones in good yields. The structures of all the synthesized compounds were characterized by 1H NMR, 13C NMR, and ES-MS spectrometry. Additionally, the crystal structures of two of these chalcones were determined by X-ray diffraction analysis.

引用

页码：768 / 773

页数：6

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